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Subject: =?utf-8?Q?Download:_Use_of_Incucyte=C2=AE_Kinase_Akt_Lentivirus_f?=
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(https://email.labxmediagroup.com/e3t/Ctc/LT+113/c3tLW04/VVTgFy5mN2j-W3TkkQ=
Y6mp8sPW4dVnpw557l3fN8SvFDj5m_5PW50kH_H6lZ3pjW56VsPD8skn7nN5nGx6RCLYZzW6v3n=
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Use of Incucyte=C2=AE Kinase Akt Lentivirus for kinetic analysis of Akt act=
ivity in living cells

Cell signaling through the Akt pathway controls numerous key cellular funct=
ions including proliferation, survival, and migration. The ability to measu=
re real-time Akt activation in living cells will provide valuable informati=
on on the involvement of Akt across multiple fields of research including o=
ncology, neuroscience, and inflammatory disease research.

In this application note (https://email.labxmediagroup.com/e3t/Ctc/LT+113/c=
3tLW04/VVTgFy5mN2j-W3TkkQY6mp8sPW4dVnpw557l3fN8SvFG43prCCW8wLKSR6lZ3k-W4NNs=
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GqW6jCPjB1kRtNgW76mFmY513LFmW26YJy51Y_4N3W1_2XjW3x_npwVHh8sc6WMsqhW144dwB21=
3NzLVBbH6y3dQv7qW6tVJHW5_3sSLW3Zfy9-497YnlW6YLXyz8VYg79f8Fk9f604 ) , we des=
cribe the use of Incucyte=C2=AE Kinase Akt Lentivirus for kinetic analysis =
of Akt activity in living cells.

Topics include:

- Assay principle and quantification methods.
- Direct and indirect inhibition of Akt signaling in Glioblastoma.
- Targeting upstream inhibitors of Akt activity.
- Regulation of Akt activity in inflammation response.
- Akt activity and cell function regulation.

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et" data-hs-cos-type=3D"module"><table class=3D"hse-image-wrapper" role=3D"=
presentation" width=3D"100%" cellpadding=3D"0" cellspacing=3D"0" style=3D"b=
order-spacing:0 !important; border-collapse:collapse; mso-table-lspace:0pt;=
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; mso-line-height-rule:exactly; font-family:Georgia, serif; color:#23286b; =
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ame=3DSartorius%20-%20image-1.jpg" style=3D"outline:none; text-decoration:n=
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e-1.jpg?upscale=3Dtrue&amp;width=3D2400&amp;upscale=3Dtrue&amp;name=3DSarto=
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padding-top:8px" bgcolor=3D"#FFFFFF">
    
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<div id=3D"column-2-0" class=3D"hse-column hse-size-12">
  <table role=3D"presentation" cellpadding=3D"0" cellspacing=3D"0" width=3D=
"100%" style=3D"border-spacing:0 !important; border-collapse:collapse; mso-=
table-lspace:0pt; mso-table-rspace:0pt"><tbody><tr><td class=3D"hs_padded" =
style=3D"border-collapse:collapse; mso-line-height-rule:exactly; font-famil=
y:Georgia, serif; font-size:18px; color:#23286b; word-break:break-word; pad=
ding:10px 20px"><div id=3D"hs_cos_wrapper_module_16239611830074" class=3D"h=
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l-type=3D"widget" data-hs-cos-type=3D"module">
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role=3D"presentation" style=3D"border-spacing:0 !important; mso-table-lspac=
e:0pt; mso-table-rspace:0pt; border-collapse:separate!important">
    <tbody><tr>
        
    
      <td align=3D"center" valign=3D"middle" bgcolor=3D"#D2232B" style=3D"b=
order-collapse:collapse; mso-line-height-rule:exactly; font-family:Georgia,=
 serif; font-size:18px; color:#23286b; word-break:break-word; border-radius=
:20px; cursor:auto; background-color:#D2232B">
   
        <a href=3D"https://email.labxmediagroup.com/e3t/Ctc/LT+113/c3tLW04/=
VVTgFy5mN2j-W3TkkQY6mp8sPW4dVnpw557l3fN8SvFDj5nR32W50kH_H6lZ3pPW2Y39084B__8=
dW6cwWNb7sqd5KW3ZSL--268wjvW5BJVl44gXzCHW2BfYJT2W5d6RW6gcJj75V7ZLjW8QMsv43k=
RLF6W6Mq0rX8xc5dCW4y_zWJ3Mr51LN9g1ZxYwdGlrW9gcfWf3T7gt7Vd2Frl3pkwP8W1hhbzW5=
rnjvxN95Szjj4V_38W837jzZ46ty6RVYd7D_587Bz9V7V0bT46zCypW6RFnHx5jlLZ2W3HDDkj4=
g9V4nW2hGScZ6l7sptW5G9_7J22hsLgW6NHJB83xK7tFW8jCj6m8T5-FhW99PqRM6_j7m-W4hZB=
Vt3QdZT7W7mR6f07TxHBJW8sp_1k56rk1fW622tBL3wKC_RW3Lb1K89hSzt_W934NqL92rZMqW5=
wKmL06ZYzDVVDH4hr5rTS4Md_zn9P04" target=3D"_blank" style=3D"color:#00a4bd; =
mso-line-height-rule:exactly; font-size:22px; font-family:Arial, sans-serif=
; Margin:0; text-transform:none; text-decoration:none; padding:12px 18px; d=
isplay:block" data-hs-link-id=3D"2">
          <strong style=3D"color:#ffffff;font-weight:normal;text-decoration=
:none;font-style:normal;">Download APPLICATION NOTE</strong>
        </a>
      </td>
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  </tbody></table>
</div></td></tr></tbody></table>
<table role=3D"presentation" cellpadding=3D"0" cellspacing=3D"0" width=3D"1=
00%" style=3D"border-spacing:0 !important; border-collapse:collapse; mso-ta=
ble-lspace:0pt; mso-table-rspace:0pt"><tbody><tr><td class=3D"hs_padded" st=
yle=3D"border-collapse:collapse; mso-line-height-rule:exactly; font-family:=
Georgia, serif; font-size:18px; color:#23286b; word-break:break-word; paddi=
ng:10px 20px"><div id=3D"hs_cos_wrapper_module_16242852582431" class=3D"hs_=
cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_module" style=3D"colo=
r: inherit; font-size: inherit; line-height: inherit;" data-hs-cos-general-=
type=3D"widget" data-hs-cos-type=3D"module"><div id=3D"hs_cos_wrapper_modul=
e_16242852582431_" class=3D"hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wra=
pper_type_rich_text" style=3D"color: inherit; font-size: inherit; line-heig=
ht: inherit;" data-hs-cos-general-type=3D"widget" data-hs-cos-type=3D"rich_=
text"><h1 style=3D"margin:0; mso-line-height-rule:exactly; font-family:Geor=
gia, serif; color:#23286b; font-size:18px; line-height:125%; text-align:cen=
ter" align=3D"center"><span style=3D"color: #000000; font-family: Arial, sa=
ns-serif;">Use of Incucyte=C2=AE Kinase Akt Lentivirus for kinetic analysis=
 of Akt activity in living cells</span></h1>
<p style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%"=
>&nbsp;</p>
<p style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%"=
><span style=3D"color: #000000;"><span style=3D"font-family: Arial, sans-se=
rif;">Cell signaling through the Akt pathway controls numerous key cellular=
 functions including proliferation, survival, and migration. The ability to=
 measure real-time Akt activation in living cells will provide valuable inf=
ormation on the involvement of Akt across multiple fields of research inclu=
ding oncology, neuroscience, and inflammatory disease research. </span></sp=
an></p>
<p style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%"=
>&nbsp;</p>
<p style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%"=
><span style=3D"color: #000000;"><span style=3D"font-family: Arial, sans-se=
rif;"><a href=3D"https://email.labxmediagroup.com/e3t/Ctc/LT+113/c3tLW04/VV=
TgFy5mN2j-W3TkkQY6mp8sPW4dVnpw557l3fN8SvFG43qgyTW8wLKSR6lZ3kNW4KcFN17mdLGjW=
138-6C48w3HmW3zsv543yVTh5W2fSt_-15ZZymVgbtcD5r26-NW8lHdWV42h62zW4wxD4T8yh7K=
9W1wG60Y2mjkk6W46PSJ33hgznGW3qpZ1M4lG0nJW8WJhP82dQcSHW4xR9qB1-_l3GW5Y0NKP1_=
HMySW6gZL8Z7hBklyW9hR5zt97XSL7W28YYGb9jVLjYW1Y2sx71k2KCwW3mN2Gy4MDrKFN2X-gb=
5t8HgdW4MzHVF26B8qGW2F0-mG6KKMSXW6MjtBd89_QvcW6gDv908FQ23mVd3pHd6-HrGTN3lJL=
VkY24CjW6X_4qP89RythW4ZkN6k4kbFWKW5yxXGp1d_QL7f101P0C04" rel=3D"noopener" s=
tyle=3D"mso-line-height-rule:exactly; color:#929eb2" data-hs-link-id=3D"0" =
target=3D"_blank">In this application note</a>, we describe the use of Incu=
cyte=C2=AE Kinase Akt Lentivirus for kinetic analysis of Akt activity in li=
ving cells. </span></span></p>
<p style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%"=
>&nbsp;</p>
<p style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%"=
><span style=3D"color: #000000;"><span style=3D"font-family: Arial, sans-se=
rif;">Topics include: </span></span></p>
<ul style=3D"mso-line-height-rule:exactly; line-height:175%; list-style-typ=
e:circle">
<li style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%=
"><span style=3D"color: #000000;"><span style=3D"font-family: Arial, sans-s=
erif;">Assay principle and quantification methods.</span></span></li>
<li style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%=
"><span style=3D"color: #000000;"><span style=3D"font-family: Arial, sans-s=
erif;">Direct and indirect inhibition of Akt signaling in Glioblastoma.</sp=
an></span></li>
<li style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%=
"><span style=3D"color: #000000;"><span style=3D"font-family: Arial, sans-s=
erif;">Targeting upstream inhibitors of Akt activity.</span></span></li>
<li style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%=
"><span style=3D"color: #000000;"><span style=3D"font-family: Arial, sans-s=
erif;">Regulation of Akt activity in inflammation response.</span></span></=
li>
<li style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%=
"><span style=3D"color: #000000;"><span style=3D"font-family: Arial, sans-s=
erif;">Akt activity and cell function regulation.</span></span></li>
</ul></div></div></td></tr></tbody></table>
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