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Subject: Download: Enhance Your Research with Real-Time Analysis of Akt Cell
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Download APPLICATION NOTE
(https://email.labxmediagroup.com/e3t/Ctc/LT+113/c3tLW04/VW089t5LY6ZMW3xyl6=
Q55KfHXW6hm-BV59ny48N24tzv25m_5PW50kH_H6lZ3pPW8LWTrW3QRr4XW7dSHsr6Jrg_mW881=
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2qN1flKH8f5HlqH004 )

Use of Incucyte=C2=AE Kinase Akt Lentivirus for kinetic analysis of Akt act=
ivity in living cells

Cell signaling through the Akt pathway controls numerous key cellular funct=
ions including proliferation, survival, and migration. The ability to measu=
re real-time Akt activation in living cells will provide valuable informati=
on on the involvement of Akt across multiple fields of research including o=
ncology, neuroscience, and inflammatory disease research.

In this application note (https://email.labxmediagroup.com/e3t/Ctc/LT+113/c=
3tLW04/VW089t5LY6ZMW3xyl6Q55KfHXW6hm-BV59ny48N24tzv25m_5PW50kH_H6lZ3pPW8LWT=
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mpWzTW5Q638C7FcltKW5HW8MG55gm2tW16mW6R7lFKFbW47sv3X5gy816W6yJxkL2y75vwW72fB=
7-2023JRW7S_4dG8M5xJZW5202qN1flKH8f5HlqH004 ) , we describe the use of Incu=
cyte=C2=AE Kinase Akt Lentivirus for kinetic analysis of Akt activity in li=
ving cells.

Topics include:

- Assay principle and quantification methods.
- Direct and indirect inhibition of Akt signaling in Glioblastoma.
- Targeting upstream inhibitors of Akt activity.
- Regulation of Akt activity in inflammation response.
- Akt activity and cell function regulation.

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presentation" width=3D"100%" cellpadding=3D"0" cellspacing=3D"0" style=3D"b=
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; mso-line-height-rule:exactly; font-family:Georgia, serif; color:#23286b; =
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ame=3DSartorius%20-%20image-1.jpg" style=3D"outline:none; text-decoration:n=
one; -ms-interpolation-mode:bicubic; border:none; max-width:100%; font-size=
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"https://viewonline.labx.com/hs-fs/hubfs/Sartorius%20-%20image-1.jpg?upscal=
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e-1.jpg?upscale=3Dtrue&amp;width=3D2400&amp;upscale=3Dtrue&amp;name=3DSarto=
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th:600px; Margin-left:auto; Margin-right:auto; border-collapse:collapse; bo=
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8px" bgcolor=3D"#FFFFFF">
    
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<div id=3D"column-2-0" class=3D"hse-column hse-size-12">
  <table role=3D"presentation" cellpadding=3D"0" cellspacing=3D"0" width=3D=
"100%" style=3D"border-spacing:0 !important; border-collapse:collapse; mso-=
table-lspace:0pt; mso-table-rspace:0pt"><tbody><tr><td class=3D"hs_padded" =
style=3D"border-collapse:collapse; mso-line-height-rule:exactly; font-famil=
y:Georgia, serif; font-size:18px; color:#23286b; word-break:break-word; pad=
ding:10px 20px"><div id=3D"hs_cos_wrapper_module_16239611830074" class=3D"h=
s_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_module" style=3D"co=
lor: inherit; font-size: inherit; line-height: inherit;" data-hs-cos-genera=
l-type=3D"widget" data-hs-cos-type=3D"module">
 =20
  <table align=3D"center" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" =
role=3D"presentation" style=3D"border-spacing:0 !important; mso-table-lspac=
e:0pt; mso-table-rspace:0pt; border-collapse:separate!important">
    <tbody><tr>
        
    
      <td align=3D"center" valign=3D"middle" bgcolor=3D"#D2232B" style=3D"b=
order-collapse:collapse; mso-line-height-rule:exactly; font-family:Georgia,=
 serif; font-size:18px; color:#23286b; word-break:break-word; border-radius=
:20px; cursor:auto; background-color:#D2232B">
   
        <a href=3D"https://email.labxmediagroup.com/e3t/Ctc/LT+113/c3tLW04/=
VW089t5LY6ZMW3xyl6Q55KfHXW6hm-BV59ny48N24tzv25nR32W50kH_H6lZ3m5W4mtJsl41BfZ=
xW7PG5W_99GBW0W3m3-ZG6V0gQQW7QqfyS95nvffW6JfmpJ5cQnyBW5cn44S6tP8pZW5mL6dF63=
092MW8SSScD24LDnjW4vqWp54TtVpXW2vdhzd3n6MT6W73P1BR4q4xDJW8pBJk91kMZ13W42RdK=
84qN9kwW1Jnv3M8mgSV9W4DZhnH2yMTs1W6_l1yM8qn-rrW1QPYC616kD_ZV4bHQR7Mjx57VX4q=
XF3Df4PGW6MnFcb3Md8NBN5Nyj5slV7YXN2GZk3mm0JMrW4-mJdz7KBTTlW4jntGn5HtJz1W79r=
Z7l3SLPQ_W13d_dV1C9HVbW43-JXw2pzCntW6SmjDP1wBB1zW6yJBN_95VL5RW8GvQQY4l5NTVV=
mwrvT72b2wKW2jWYQ77Z_bjNf7tCQ0404" target=3D"_blank" style=3D"color:#00a4bd=
; mso-line-height-rule:exactly; font-size:22px; font-family:Arial, sans-ser=
if; Margin:0; text-transform:none; text-decoration:none; padding:12px 18px;=
 display:block" data-hs-link-id=3D"2">
          <strong style=3D"color:#ffffff;font-weight:normal;text-decoration=
:none;font-style:normal;">Download APPLICATION NOTE</strong>
        </a>
      </td>
    </tr>
  </tbody></table>
</div></td></tr></tbody></table>
<table role=3D"presentation" cellpadding=3D"0" cellspacing=3D"0" width=3D"1=
00%" style=3D"border-spacing:0 !important; border-collapse:collapse; mso-ta=
ble-lspace:0pt; mso-table-rspace:0pt"><tbody><tr><td class=3D"hs_padded" st=
yle=3D"border-collapse:collapse; mso-line-height-rule:exactly; font-family:=
Georgia, serif; font-size:18px; color:#23286b; word-break:break-word; paddi=
ng:10px 20px"><div id=3D"hs_cos_wrapper_module_16242852582431" class=3D"hs_=
cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_module" style=3D"colo=
r: inherit; font-size: inherit; line-height: inherit;" data-hs-cos-general-=
type=3D"widget" data-hs-cos-type=3D"module"><div id=3D"hs_cos_wrapper_modul=
e_16242852582431_" class=3D"hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wra=
pper_type_rich_text" style=3D"color: inherit; font-size: inherit; line-heig=
ht: inherit;" data-hs-cos-general-type=3D"widget" data-hs-cos-type=3D"rich_=
text"><h1 style=3D"margin:0; mso-line-height-rule:exactly; font-family:Geor=
gia, serif; color:#23286b; font-size:18px; line-height:125%; text-align:cen=
ter" align=3D"center"><span style=3D"color: #000000; font-family: Arial, sa=
ns-serif;">Use of Incucyte=C2=AE Kinase Akt Lentivirus for kinetic analysis=
 of Akt activity in living cells</span></h1>
<p style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%"=
>&nbsp;</p>
<p style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%"=
><span style=3D"color: #000000;"><span style=3D"font-family: Arial, sans-se=
rif;">Cell signaling through the Akt pathway controls numerous key cellular=
 functions including proliferation, survival, and migration. The ability to=
 measure real-time Akt activation in living cells will provide valuable inf=
ormation on the involvement of Akt across multiple fields of research inclu=
ding oncology, neuroscience, and inflammatory disease research. </span></sp=
an></p>
<p style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%"=
>&nbsp;</p>
<p style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%"=
><span style=3D"color: #000000;"><span style=3D"font-family: Arial, sans-se=
rif;"><a href=3D"https://email.labxmediagroup.com/e3t/Ctc/LT+113/c3tLW04/VW=
089t5LY6ZMW3xyl6Q55KfHXW6hm-BV59ny48N24tzv25nR32W50kH_H6lZ3l-W5lTnxb183kbNW=
41JT0T5xfMSTW50vCB36vTnsdW7rGdV83tqLmKVDWZt26_F2F5W5K_FRn7XTjVVW5CSLwx76j6x=
6VgPb4C1jH4yfW51fw8B8256ywN1tgDQmRL39pW6gR7nh5nypmBW6YktvV5HgSxPN57Zv3KcdcT=
sW61YnqY3YRZtpW88JLCr4yBMGDW6Z9m7N1T-nF_W22fWfy8H5T6DW3BndRP4zYtnPW7Ysdl97p=
54ltW1f7K8026zMygW2pDrVN4SFXhdVy34vW4brgmCN1l0thb24H7mVYdcgr7GYN25W6-xphB1S=
fYB9W28w5jP9fKB04W6BFFDV8f1VTrW7qky6B8zYszzW5zwfRs89NQXqW3qCMl14Xt0LhW8LpYq=
k36wrHxW3vsbDG1w7MhFf3HNwL204" rel=3D"noopener" style=3D"mso-line-height-ru=
le:exactly; color:#929eb2" data-hs-link-id=3D"3" target=3D"_blank">In this =
application note</a>, we describe the use of Incucyte=C2=AE Kinase Akt Lent=
ivirus for kinetic analysis of Akt activity in living cells. </span></span>=
</p>
<p style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%"=
>&nbsp;</p>
<p style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%"=
><span style=3D"color: #000000;"><span style=3D"font-family: Arial, sans-se=
rif;">Topics include: </span></span></p>
<ul style=3D"mso-line-height-rule:exactly; line-height:175%; list-style-typ=
e:circle">
<li style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%=
"><span style=3D"color: #000000;"><span style=3D"font-family: Arial, sans-s=
erif;">Assay principle and quantification methods.</span></span></li>
<li style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%=
"><span style=3D"color: #000000;"><span style=3D"font-family: Arial, sans-s=
erif;">Direct and indirect inhibition of Akt signaling in Glioblastoma.</sp=
an></span></li>
<li style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%=
"><span style=3D"color: #000000;"><span style=3D"font-family: Arial, sans-s=
erif;">Targeting upstream inhibitors of Akt activity.</span></span></li>
<li style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%=
"><span style=3D"color: #000000;"><span style=3D"font-family: Arial, sans-s=
erif;">Regulation of Akt activity in inflammation response.</span></span></=
li>
<li style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%=
"><span style=3D"color: #000000;"><span style=3D"font-family: Arial, sans-s=
erif;">Akt activity and cell function regulation.</span></span></li>
</ul></div></div></td></tr></tbody></table>
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