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Envelope-to: pamay@sapasequipment.com
Delivery-date: Mon, 22 Aug 2022 14:25:29 -0400
Date: Mon, 22 Aug 2022 11:24:45 -0700
From: Molecular Devices <info@moldev.com>
Reply-To: info@moldev.com
To: pamay@sapasequipment.com
Message-ID: <1661189482317.fad1ea5f-3321-41a3-9b06-35e63405b51b@20222769m.moldev.com>
Subject: NEW App Note: Detect endotoxin with the Kinetic-QCL Kinetic
 Chromogenic LAL Assay
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Detect endotoxin with SpectraMax Mini

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cCW9dBCLv82zsKKW2vWkXT3H02B0W8SpLjX32zQXrVQzm1D87Vy873grM1 )

NEW

Application Note

Monitoring for contaminants is a critical step during the production proces=
s in the pharmaceutical and medical device industries. A frequent contamina=
nt, endotoxin, can cause fever, inflammation, headache, nausea, and even de=
ath. Found in the cell wall of gram-negative bacteria, endotoxin has routin=
ely been detected by the sensitive and specific Limulus Amebocyte Lysate (L=
AL) assay.

This application note demonstrates the suitability of the SpectraMax=C2=AE =
Mini reader and LAL Kinetic- QCL Assay in endotoxin quantitation.

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style=3D"border-collapse:collapse; mso-line-height-rule:exactly; font-famil=
y:Arial, sans-serif; font-size:14px; color:#6a747c; word-break:break-word; =
padding:10px 20px 0px"><div id=3D"hs_cos_wrapper_module-0-1-0" class=3D"hs_=
cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_module" style=3D"colo=
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it;" data-hs-cos-general-type=3D"widget" data-hs-cos-type=3D"rich_text"><h1=
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16px; line-height:150%; text-align:right" align=3D"right">Detect endotoxin =
with the SpectraMax Mini</h1></div></div></td></tr></tbody></table>
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00%" style=3D"border-spacing:0 !important; border-collapse:collapse; mso-ta=
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g-left:10px; padding-right:10px">
   =20
   =20
    
      <div class=3D"hse-column-container" style=3D"min-width:280px; max-wid=
th:600px; width:100%; Margin-left:auto; Margin-right:auto; border-collapse:=
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<div id=3D"column-0-0" class=3D"hse-column hse-size-12">
  <table role=3D"presentation" cellpadding=3D"0" cellspacing=3D"0" width=3D=
"100%" style=3D"border-spacing:0 !important; border-collapse:collapse; mso-=
table-lspace:0pt; mso-table-rspace:0pt"><tbody><tr><td class=3D"hs_padded" =
style=3D"border-collapse:collapse; mso-line-height-rule:exactly; font-famil=
y:Arial, sans-serif; font-size:14px; color:#6a747c; word-break:break-word; =
padding:10px 35px 30px"><div id=3D"hs_cos_wrapper_module_166083911264016" c=
lass=3D"hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_module" st=
yle=3D"color: inherit; font-size: inherit; line-height: inherit;" data-hs-c=
os-general-type=3D"widget" data-hs-cos-type=3D"module"><div id=3D"hs_cos_wr=
apper_module_166083911264016_" class=3D"hs_cos_wrapper hs_cos_wrapper_widge=
t hs_cos_wrapper_type_rich_text" style=3D"color: inherit; font-size: inheri=
t; line-height: inherit;" data-hs-cos-general-type=3D"widget" data-hs-cos-t=
ype=3D"rich_text"><h1 style=3D"margin:0; mso-line-height-rule:exactly; line=
-height:150%; font-size:22px; color:#75ac58; font-family:'ProximaNova', Ari=
al, sans-serif">NEW</h1>
<h2 style=3D"margin:0; mso-line-height-rule:exactly; line-height:150%; font=
-size:16px; color:#3692ab; font-family:'ProximaNova', Arial, sans-serif">Ap=
plication Note</h2>
<p style=3D"mso-line-height-rule:exactly; line-height:100%">&nbsp;</p>
<p style=3D"mso-line-height-rule:exactly; line-height:150%">Monitoring for =
contaminants is a critical step during the production process in the pharma=
ceutical and medical device industries. A frequent contaminant, endotoxin, =
can cause fever, inflammation, headache, nausea, and even death. Found in t=
he cell wall of gram-negative bacteria, endotoxin has routinely been detect=
ed by the sensitive and specific Limulus Amebocyte Lysate (LAL) assay.</p>
<p style=3D"mso-line-height-rule:exactly; line-height:150%">&nbsp;</p>
<p style=3D"mso-line-height-rule:exactly; line-height:150%">This <span styl=
e=3D"color: #75ac34;"><a href=3D"https://email.moleculardevices.com/e3t/Ctc=
/OR+113/d2nr5L04/VXhw903tS9ZmW5-QB9c8qcj-pV_gMC14P1J5SN2QYvzX5nCVVV3Zsc37Cg=
V5GW3Vv1Wm65-RdFVRLxf21ts8YNW7fD7TF2B-TTVW1-3HL_7kfPHQW7gsCHj6FlF-YN5_WWMmd=
q3lfW50_sPR7dLG-LW3jdSnX5fTtRmW993Dmg2tjsLsW5pd1tP1n_PzXW2tRK5g6J5NJnW8D3zw=
c8FbVLCMgbqThhsW_DN9gX6f1smJBVW1s4PdR857X8lW5Jf5lF2pLxD4VhGhw03Px9z6W10Nqsq=
7cTwYxVHYSJ06TvcdtN32yTS7-5yJ2W1M1hRM46NFlRW9fZQ-V2qSkLkW7zD-356Cz93nW3h1x-=
F1SRRGXW6mrqyJ3LM43SW4KSgX781DScCW4qfvmm32J7mpW9dy5wW1qQ2xBW3H9Cdz7FzZ6yW3F=
SRMv999vtmW7LzY502CbqhdN92LkSb30JmPW3KWmf73cBJ24W1xtr-B4-zRkwW8RHBLh8Bd5ZbW=
7HNqzk7k_qNMW2dvzH28gV9r2W3m1Npq6l4hL1W88jmkN76qFJ-W3z6JJB57WP2R3gj01" styl=
e=3D"mso-line-height-rule:exactly; text-decoration:none; color:#75ac34; fon=
t-weight:bold" rel=3D"noopener" data-hs-link-id=3D"1" target=3D"_blank">app=
lication note</a></span> demonstrates the suitability of the SpectraMax=C2=
=AE Mini reader and LAL Kinetic- QCL Assay in endotoxin quantitation.</p></=
div></div></td></tr></tbody></table>
</div>


    
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  =20
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  <div id=3D"section-5" class=3D"hse-section" style=3D"padding-left:10px; p=
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table-lspace:0pt; mso-table-rspace:0pt"><tbody><tr><td class=3D"hs_padded" =
style=3D"border-collapse:collapse; mso-line-height-rule:exactly; font-famil=
y:Arial, sans-serif; font-size:14px; color:#6a747c; word-break:break-word; =
padding:10px 20px"><div id=3D"hs_cos_wrapper_module-5-0-0" class=3D"hs_cos_=
wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_module" style=3D"color: i=
nherit; font-size: inherit; line-height: inherit;" data-hs-cos-general-type=
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" cellpadding=3D"0" cellspacing=3D"0" style=3D"border-spacing:0 !important;=
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h:260px; background:linear-gradient(to right, rgba(117,172,88,1) 0%, rgba(9=
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      <td align=3D"center" height=3D"45" style=3D"border-collapse:collapse;=
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YjW5_hxxl8s37BxW3Z9zbq3tnzq0W7BRRC94D7--jW5JzDG17zYtMQW1PJlQW1Kd-YDW771xml2=
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