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Envelope-to: pamay@sapasequipment.com
Delivery-date: Wed, 13 Nov 2024 12:33:22 -0400
Date: Wed, 13 Nov 2024 08:32:38 -0800
From: Molecular Devices <info@moldev.com>
Reply-To: info@moldev.com
To: pamay@sapasequipment.com
Message-ID: <1731515557757.cf8d119e-a182-4abb-94df-22009ef49744@20222769m.moldev.com>
Subject: =?utf-8?Q?November_Newsletter:_As_the_holiday_season_appro?=
 =?utf-8?Q?aches,_we=E2=80=99re_here_to_bring_some_cheer_to_your_lab?=
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View in browser (https://email.moleculardevices.com/e3t/Ctc/OR+113/d2nr5L04=
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bW3sPDqN269phdW2wVWp094Lkvdf4p1N5604 )

Welcome to the November edition of our newsletter!

For 40 years, we=E2=80=99ve helped scientists harness the full potential of=
 biology with next-generation technology. Here we share the latest in autom=
ated, end-to-end solutions that span research disciplines to advance scient=
ific discovery and improve the quality of human life worldwide.

____________________________________________________

UPGRADE BEFORE THE NEW YEAR
Secure Your New Automation System by Year-End and Save!

As the holiday season approaches, we=E2=80=99re here to bring some cheer to=
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eceive two days of FREE hands-on training in Q1 2025 to ensure you=E2=80=99=
re ready to hit the ground running.

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ects faster and more efficiently.
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 be waiting for equipment or support.

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(https://email.moleculardevices.com/e3t/Ctc/OR+113/d2nr5L04/VWZvKy5P_ypjN6T=
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3j1jqb3-L01nW8mlxzJ4_tPh_N69qm6XRKD1-W5wZc6M6FPsn8W8gt9Yp1_H8L7W89xW6v4ssDq=
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1hspDjW1mRbD_1NJ06NV_BCb57SxBNCN1NGy03pwSbCW2ZfD6Y1KmdjlW1wcBj614ddW_W5Br2n=
94GQvDfW8nJRGK7PQ8WhN3X6xDR4hPDsf65M-cg04 )

____________________________________________________

T-CELLS AND 3D CELL MODELS FOR IMMUNOTHERAPY
Using the power of T-cells with organoids and spheroids for cancer therapy =
and research

Immunotherapy, which leverages the immune system to specifically target can=
cer cells, is gaining traction as an additional form of cancer treatment. T=
hese therapies include CAR T-cells (Chimeric Antigen Receptor engineered T-=
cells), tumor-infiltrating lymphocytes (TIL), and other genetically modifie=
d T-cells.

Enhancing T-cell recruitment and cytotoxic activity is crucial for successf=
ul cancer immunotherapy. In preclinical scientific research, 3D cell models=
 offer advantages over 2D monolayer cultures by better mimicking the immuno=
suppressive tumor microenvironment (TME). For example, patient-derived orga=
noids (PDOs) are superior to traditional 2D monolayer cultures because they=
 better replicate the physical and chemical cues of the TME.

Explore T-cells
(https://email.moleculardevices.com/e3t/Ctc/OR+113/d2nr5L04/VWZvKy5P_ypjN6T=
66-F1d8t1W2v98dD5nlhlVN4zFKKY5fkwKW5BWr2F6lZ3mLW1l7G601r4wTpW59Ldcd8z2xG8W2=
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R3Z3CYqRMW2JNBPN4RjNnsW7ZYjV32kyrqdf1VjJ8d04 )

____________________________________________________

NEW DRUG DISCOVERY WORLD ARTICLE
Are FDA plans enough to boost inclusivity within clinical trials?

In an effort to address diversity in clinical trials, the FDA recently issu=
ed draft guidance mandating sponsors to create Diversity Action Plans, aime=
d at engaging historically underrepresented populations. These plans encour=
age enrollment goals and strategies tailored to the unique needs of various=
 communities, aiming to ensure therapies reflect the populations that will =
ultimately use them.

In this article, Molecular Devices' VP of Strategy and Innovation, Shantanu=
 Dhamija, emphasizes that advanced technologies like induced pluripotent st=
em cells (iPSCs) could help alleviate concerns about drug safety in diverse=
 populations. This approach could drive greater participation by providing =
data on how different demographics respond to therapies, ultimately improvi=
ng access and outcomes across healthcare.

Read article
(https://email.moleculardevices.com/e3t/Ctc/OR+113/d2nr5L04/VWZvKy5P_ypjN6T=
66-F1d8t1W2v98dD5nlhlVN4zFKKF5jGjMW50kH_H6lZ3nDVSYbvs14BQSfW2DT6Ty58kpkmW2X=
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zW3cp0Sw2yXJszW35tM7q3lNQPHW4bdfYY6WZX_GW8K94_62-V5bfW9kygT58NBf-0W6xk9T31x=
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W1fMjs5dBXjsM04 )

____________________________________________________

Is you lab effectively equipped to help you make your next big discovery?
We know you have big things planned in the new year, but do you have the ri=
ght tools to reach your goals? We'd like to support your success and help y=
ou hit the ground running in the new year with significant savings on the p=
urchase of a new cellular imaging solution.

Combine the options and modules that address your specific research - inclu=
ding objectives, filters, imaging modes, and environmental conditions - to =
create the perfect automated solution that supports your applications, incr=
eases throughput, and streamlines workflows.

Secure your discount
(https://email.moleculardevices.com/e3t/Ctc/OR+113/d2nr5L04/VWZvKy5P_ypjN6T=
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J0VNW2K4FkK59vrF_W7NvvjH8KhLB_W75NzSB1J4GtLN5K_r94W1_pLW2d5H-45NDCtRN6Rx0j0=
br-4ZW3jm4wm2Pzz_HW26bLPC29cJ2dW6hrVz-3R3rtTW1wd1GY1gnq_3VQKXnk6660kKW1PzK_=
w2dJZTDW6MCg8Z1yVXrYN8DNgSQVVtwRW6jqhjZ8l1P1kVzNc7_67MZjrN4MPYB-1H0vbW6_rtQ=
q4-CM7zf59QNXT04 )

____________________________________________________

NEW APPLICATION NOTE
Increase assay robustness by tracking a drug's chronic effect on cardiac fu=
nction over extended periods of time

In this application note, we demonstrate an in vitro model using iPSC-CMs c=
onstantly expressing a genetically encoded calcium indicator for monitoring=
 cell responses to various compounds for an extended period of time (up to =
60 days).

Additionally, an optogenetic actuator was used to pace the cardiomyocytes i=
n a noninvasive and reversible manner, mimicking a physiological steady rhy=
thm.

This contactless control and recording of cardiomyocytes cannot be easily a=
chieved through conventional electrical stimulation.

Download application note
(https://email.moleculardevices.com/e3t/Ctc/OR+113/d2nr5L04/VWZvKy5P_ypjN6T=
66-F1d8t1W2v98dD5nlhlVN4zFKKF7cV0WW50l5tj6lZ3pLN1hQb_QkwJRCW1d4C7D73GrZfW7r=
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rD5FkW3Sksjv8V53DyW79RF5F4ytzhgW240hmk3xrkR7W7rYbmh8rvjpvW7sRvhD4-_sCWW6VqZ=
lP4lhlNLW1WYdnj6j5n1WW3fmL3t7VN7gyW6VTy5D3BmQGrW3gTNlv3tJjvfW7_VrmW7sndMQW5=
sYp5N78dGRcW6yXRS26tSmG8W7wXx3_6fnCjlW3-0lF08YvxV_W7v7NTS4dXZTZdWMnjj04 )

____________________________________________________

NEW LAUNCH
We are excited to announce the launch of SoftMax Pro 7.3.1 Software and Sof=
tMax Pro 7.3.1 GxP Software Suite!

SoftMax=C2=AE Pro 7.3.1 Standard and GxP Software include several new featu=
res, formula updates, and enhancements.

Key features included in the Standard and GxP edition:

- Fully validated with Windows 11 Enterprise and Windows 11 Professional 23=
H2; Windows Server 2022; Microsoft SQL Server 2022
- Bulk Export feature features the ability to export multiple documents fro=
m different folders with included support via the Automation API.
- Tool tips translated into Simplified Chinese.

Update your software
(https://email.moleculardevices.com/e3t/Ctc/OR+113/d2nr5L04/VWZvKy5P_ypjN6T=
66-F1d8t1W2v98dD5nlhlVN4zFKLd5fkwKW69t95C6lZ3mgW3RQ1jz3T09xDN58cFgDh47yqW1M=
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tTL74-J3GVf0Zlt7s8_30N61pfdXWWW9hW1qJt_c8wFz63W28RjHm4fwP48f32cNT004 )

____________________________________________________

EVENTS

Cell Bio (ASCB)  (https://email.moleculardevices.com/e3t/Ctc/OR+113/d2nr5L0=
4/VWZvKy5P_ypjN6T66-F1d8t1W2v98dD5nlhlVN4zFKLR3l5QzW7lCdLW6lZ3n_N8-CFgY7f3C=
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wWW2FKn0K7B6d6SN88Nf6NyQ_B0W5qxN6t6gBQ_NW6GSKCW8txHhHN3WxfZGgjVnZW6D_sG29lZ=
RnFVC9mqm57XBBzW61j88H8gR8jSW2kM6q38CLCrbN5z-gsfYkrtwN57txs4f6w8hW48SMSh87Q=
HSwW6J9S156sTvkfVj9rMN352NHnW5N1wQq6vvk0HW3NPGRx6B5Gm4W4NZ19L4GnFTJdwk6Xb04=
 )

December 14-18, 2024 | San Diego, CA

____________________________________________________

JOIN OUR TEAM

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rapper_widget hs_cos_wrapper_type_module" style=3D"color: inherit; font-siz=
e: inherit; line-height: inherit;" data-hs-cos-general-type=3D"widget" data=
-hs-cos-type=3D"module"><div id=3D"hs_cos_wrapper_module-2-0-0_" class=3D"h=
s_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_rich_text" style=3D=
"color: inherit; font-size: inherit; line-height: inherit;" data-hs-cos-gen=
eral-type=3D"widget" data-hs-cos-type=3D"rich_text"><p style=3D"mso-line-he=
ight-rule:exactly; line-height:150%; font-weight:bold"><span style=3D"color=
: #000000;">Welcome to the November edition of our newsletter!</span></p>
<p style=3D"mso-line-height-rule:exactly; line-height:150%; font-weight:nor=
mal"><span style=3D"color: #000000;">For 40 years, we=E2=80=99ve helped sci=
entists harness the full potential of biology with next-generation technolo=
gy. Here we share the latest in automated, end-to-end solutions that span r=
esearch disciplines to advance scientific discovery and improve the quality=
 of human life worldwide.</span></p></div></div></td></tr></tbody></table>
<div id=3D"hs_cos_wrapper_module-3-0-0" class=3D"hs_cos_wrapper hs_cos_wrap=
per_widget hs_cos_wrapper_type_module" style=3D"color: inherit; font-size: =
inherit; line-height: inherit;" data-hs-cos-general-type=3D"widget" data-hs=
-cos-type=3D"module"><table class=3D"hse-image-wrapper" role=3D"presentatio=
n" width=3D"100%" cellpadding=3D"0" cellspacing=3D"0">
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_cos_wrapper_widget hs_cos_wrapper_type_module" style=3D"color: inherit; fo=
nt-size: inherit; line-height: inherit;" data-hs-cos-general-type=3D"widget=
" data-hs-cos-type=3D"module"><table class=3D"hse-image-wrapper" role=3D"pr=
esentation" width=3D"100%" cellpadding=3D"0" cellspacing=3D"0">
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ZVW27JCVF8FT4dqW2PrYM86rQmyDW6YSS4x8GvfkHV7Wc5w5mydpsW4vfwJF1VJVlGW56sdc91t=
ybv9W6r0Qrk981XBFW2y4smw3ybLp7W1zQRyX6VmsvGW447c3l7_bSVCW1TH3nM39Hdh7W7yX5h=
j8LHvvmN7Wv534VPtd6V5_WHp425HKXN5qksyhYTTklVyZvcV1b25ssW2LxVxW7bf4DtVpSznK6=
lLRnqN675Wp6V6mGsN3cHT2hcrpQ2W3c-Hz43QQ6C9W6PjbSH1qDk1ZW3M_fSt7WmShQW2PKMz1=
2lnbKzW8CXD1_62QpqxW2Tr4wQ7Bj783W1p41lL3d2M5_W8XYxz63mzdM3W3NcSMw1tv44rW5rX=
r4y2dW-FHW61v8kw6Zkkr-W6cvjB66BYcB1W50hrZk9j3q6DW8nKWBq1BWGD7W85QfTm7HgWX8W=
3lwS8P8SfNb3W1xSXHh4TDgt7f4GR8mg04" target=3D"_blank" style=3D"color:#00a4b=
d" data-hs-link-id=3D"0">
        <img alt=3D"Unwrap a Limited-Time offer!" src=3D"https://email.mole=
culardevices.com/hs-fs/hubfs/Screenshot%202024-11-12%20at%209.32.57%20AM.pn=
g?width=3D1120&amp;upscale=3Dtrue&amp;name=3DScreenshot%202024-11-12%20at%2=
09.32.57%20AM.png" style=3D"outline:none; text-decoration:none; border:none=
; max-width:100%; font-size:16px" width=3D"560" align=3D"middle">
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</table></div>
<table role=3D"presentation" cellpadding=3D"0" cellspacing=3D"0" width=3D"1=
00%"><tbody><tr><td class=3D"hs_padded" style=3D"font-family:Arial, sans-se=
rif; font-size:14px; color:#6a747c; word-break:break-word; padding:10px 20p=
x"><div id=3D"hs_cos_wrapper_module_17151177420832" class=3D"hs_cos_wrapper=
 hs_cos_wrapper_widget hs_cos_wrapper_type_module" style=3D"color: inherit;=
 font-size: inherit; line-height: inherit;" data-hs-cos-general-type=3D"wid=
get" data-hs-cos-type=3D"module"><div id=3D"hs_cos_wrapper_module_171511774=
20832_" class=3D"hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_r=
ich_text" style=3D"color: inherit; font-size: inherit; line-height: inherit=
;" data-hs-cos-general-type=3D"widget" data-hs-cos-type=3D"rich_text"><h2 s=
tyle=3D"margin:0; mso-line-height-rule:exactly; color:#3692ab; font-size:18=
px; line-height:150%"><span style=3D"color: #6eb43f;">UPGRADE BEFORE THE NE=
W YEAR&nbsp;</span></h2>
<h1 style=3D"margin:0; mso-line-height-rule:exactly; color:#75ac58; font-si=
ze:18px; line-height:150%"><span style=3D"color: #2b87a0;"><strong>Secure Y=
our New Automation System by Year-End and Save!&nbsp;</strong></span></h1>
<p style=3D"mso-line-height-rule:exactly; line-height:150%">&nbsp;</p>
<p style=3D"mso-line-height-rule:exactly; line-height:150%">As the holiday =
season approaches, we=E2=80=99re here to bring some cheer to your lab=E2=80=
=94kick off 2025 with a brand-new automation system, delivered by December =
31! With this exclusive holiday offer, you=E2=80=99ll also receive&nbsp;<em=
>two days of FREE hands-on training</em>&nbsp;in Q1 2025 to ensure you=E2=
=80=99re ready to hit the ground running.</p>
<p style=3D"mso-line-height-rule:exactly; line-height:150%">&nbsp;</p>
<h2 style=3D"margin:0; mso-line-height-rule:exactly; line-height:150%; font=
-size:16px; color:#3692ab">Why Act Now?</h2>
<p style=3D"mso-line-height-rule:exactly; line-height:150%">By securing you=
r system and training now, you=E2=80=99ll:</p>
<ul style=3D"mso-line-height-rule:exactly; line-height:150%">
<li><span style=3D"color: #2b87a0;"><strong>Maximize Your Budget:</strong><=
/span>&nbsp;Invest in essential equipment before year-end, optimizing this =
year=E2=80=99s budget.</li>
<li><span style=3D"color: #2b87a0;"><strong>Minimize Downtime:&nbsp;</stron=
g></span>Get up and running quickly with trained staff, reducing the time a=
nd resources often lost during onboarding.</li>
<li><span style=3D"color: #2b87a0;"><strong>Accelerate Your Research Goals:=
</strong>&nbsp;</span>Begin 2025 fully prepared, advancing projects faster =
and more efficiently.</li>
<li><span style=3D"color: #2b87a0;"><strong>Gain a Competitive Edge:</stron=
g></span>&nbsp;Start the year prepared while others might still be waiting =
for equipment or support.</li>
</ul></div></div></td></tr></tbody></table>
</div>


    
    </div>
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  </div>
  <div id=3D"section_1731425962932" class=3D"hse-section" style=3D"padding-=
left:10px; padding-right:10px">
   =20
   =20
    
      <div class=3D"hse-column-container" style=3D"min-width:280px; max-wid=
th:600px; Margin-left:auto; Margin-right:auto; background-color:#ffffff" bg=
color=3D"#ffffff">
    
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<div id=3D"column_1731425962932_0" class=3D"hse-column hse-size-6">
  <div id=3D"hs_cos_wrapper_module_173142598908210" class=3D"hs_cos_wrapper=
 hs_cos_wrapper_widget hs_cos_wrapper_type_module" style=3D"color: inherit;=
 font-size: inherit; line-height: inherit;" data-hs-cos-general-type=3D"wid=
get" data-hs-cos-type=3D"module"><table class=3D"hse-image-wrapper" role=3D=
"presentation" width=3D"100%" cellpadding=3D"0" cellspacing=3D"0">
  <tbody>
    <tr>
      <td class=3D"hs_padded" align=3D"center" valign=3D"top" style=3D"font=
-family:Arial, sans-serif; color:#6a747c; word-break:break-word; text-align=
:center; padding:10px 20px; font-size:0px">
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04/VWZvKy5P_ypjN6T66-F1d8t1W2v98dD5nlhlVN4zFKLR5g8s-W7lCGcx6lZ3n9W6nVG158Yp=
-g0W93_XZ_8NjKqBW7Xf0gx3hcRq-W8TsbWx4gbT96W2VVK5Q2fJC5VW8rwg5z4vkzmGW7lYQmX=
6MmmbZW4jYV_V6-5-wQW3smVXW7JwWhKW8738yd13YDhYW6JSXzk4GTvpHVSFKyB8SLgmPW64KZ=
Sr4SDNmGW5N6dmh1spWs2W32qJC48J9RqQVSb3py4xKGd0W1yj5Xx1fWGgwN6QNKQkS7rrrW1yd=
8MN7yd50HVSmv4T6WmM6jW8XYfyK2yrxnXW1QNkYF60Q7K4N6ZqGlxZrwTsW4_DWMh3zsCMxW2Z=
rWSp4LHyBJW1fk0R846T4D-W6-Q9kj4krQjTW16rrKj38t6XhW25LPlN91rsWBW2Qvj6n17zQ5S=
W5x-Cfs4QS05lW24_HLf5FQnhhW2nrF7T5H_cQLMCSXHm_lk-KW3qDMcH8rjnFxVn1wph4mR6PD=
W2R7Rd05nzSTPW5lVTHW2Tfs-yN2XjJsR4g128W2TtdS_1GtGSjdC21tK04" target=3D"_bla=
nk" style=3D"color:#00a4bd" data-hs-link-id=3D"0">
        <img alt=3D"Limited Time offer!" src=3D"https://email.moleculardevi=
ces.com/hs-fs/hubfs/qpixfront-1.jpg?width=3D520&amp;upscale=3Dtrue&amp;name=
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e; max-width:100%; font-size:16px" width=3D"260" align=3D"middle">
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</div>




<div id=3D"column_1731425962932_1" class=3D"hse-column hse-size-6">
  <div id=3D"hs_cos_wrapper_module_173142599212211" class=3D"hs_cos_wrapper=
 hs_cos_wrapper_widget hs_cos_wrapper_type_module" style=3D"color: inherit;=
 font-size: inherit; line-height: inherit;" data-hs-cos-general-type=3D"wid=
get" data-hs-cos-type=3D"module"><table class=3D"hse-image-wrapper" role=3D=
"presentation" width=3D"100%" cellpadding=3D"0" cellspacing=3D"0">
  <tbody>
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      <td class=3D"hs_padded" align=3D"center" valign=3D"top" style=3D"font=
-family:Arial, sans-serif; color:#6a747c; word-break:break-word; text-align=
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04/VWZvKy5P_ypjN6T66-F1d8t1W2v98dD5nlhlVN4zFKLR5g8s-W7lCGcx6lZ3pCW4tJF0y6DR=
pzmVsbm3Y34NwbkW5Sb4Y16pvMqWW4kdZHH3ZF8RDW1KtrpN5Mtfg3W11Y9hf29RcF_W3tHskF4=
mlJ5sW5y6CY64nqm9dW9c_zLB5x4CwqW1XnhPQ6WmcMjN1ZJC1h2chwwVcc1S95_4zWCMDkN8Kc=
GWYmN5SP7DPwm1nyW4d_nS442rcmxW6CmlPB3dckY5W62F8V91Yh-GVW1j1Bnj720KgRW20_jf7=
2MZcKbW5sWwMT9hnLVdW3gSf3K5dqPCfW81695427jj8WN6cV6B_80BwvW1kg2qB2x6G8DN3SGn=
6XJ5TmcW8NzVwq75LdH1W8m1BC15nR0ScW1GhYf85rTRSCVfCs8_8NgsyPW7F5yhv206jSPW7Pb=
0N26nl3PKW70MHh87skpNkW98yyPT7lfVkNW4nngT91l6Ll-W547MwD7W_5wCW4rMMPt3GTLvZW=
20GwTw44SywWW3wS0nw8zR06sN97VQD7shKJjW8y79FZ5ZbrMff1jdB6C04" target=3D"_bla=
nk" style=3D"color:#00a4bd" data-hs-link-id=3D"0">
        <img alt=3D"Secure your discount" src=3D"https://email.moleculardev=
ices.com/hs-fs/hubfs/IXM_LPX220v2-1.jpg?width=3D520&amp;upscale=3Dtrue&amp;=
name=3DIXM_LPX220v2-1.jpg" style=3D"outline:none; text-decoration:none; bor=
der:none; max-width:100%; font-size:16px" width=3D"260" align=3D"middle">
        </a>
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</div>


    
    </div>
  =20
  </div>
  <div id=3D"section_1731426028075" class=3D"hse-section" style=3D"padding-=
left:10px; padding-right:10px">
   =20
   =20
    
      <div class=3D"hse-column-container" style=3D"min-width:280px; max-wid=
th:600px; Margin-left:auto; Margin-right:auto; background-color:#ffffff" bg=
color=3D"#ffffff">
    
   =20
    
    

<div id=3D"column_1731426028075_0" class=3D"hse-column hse-size-12">
  <table role=3D"presentation" cellpadding=3D"0" cellspacing=3D"0" width=3D=
"100%"><tbody><tr><td class=3D"hs_padded" style=3D"font-family:Arial, sans-=
serif; font-size:14px; color:#6a747c; word-break:break-word; padding:10px 2=
0px"><div id=3D"hs_cos_wrapper_module_173142603210312" class=3D"hs_cos_wrap=
per hs_cos_wrapper_widget hs_cos_wrapper_type_module" style=3D"color: inher=
it; font-size: inherit; line-height: inherit;" data-hs-cos-general-type=3D"=
widget" data-hs-cos-type=3D"module"><div id=3D"hs_cos_wrapper_module_173142=
603210312_" class=3D"hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_ty=
pe_rich_text" style=3D"color: inherit; font-size: inherit; line-height: inh=
erit;" data-hs-cos-general-type=3D"widget" data-hs-cos-type=3D"rich_text"><=
div style=3D"mso-line-height-rule:exactly; line-height:150%">
<div style=3D"mso-line-height-rule:exactly; line-height:150%">
<div style=3D"mso-line-height-rule:exactly; line-height:150%">
<div data-hs-cos-general-type=3D"widget" data-hs-cos-type=3D"module" style=
=3D"mso-line-height-rule:exactly; line-height:150%">
<div data-hs-cos-general-type=3D"widget" data-hs-cos-type=3D"rich_text" sty=
le=3D"mso-line-height-rule:exactly; line-height:150%">
<h2 style=3D"margin:0; mso-line-height-rule:exactly; line-height:150%; font=
-size:16px; color:#3692ab">How to Unwrap This Offer:</h2>
<p style=3D"mso-line-height-rule:exactly; line-height:150%">By securing you=
r system and training now, you=E2=80=99ll:</p>
<ul style=3D"mso-line-height-rule:exactly; line-height:150%">
<li>Review your budget and identify workflow needs</li>
<li>Choose the Molecular Devices automation system that will elevate your r=
esearch</li>
<li>Place your order by&nbsp;<strong>November 22, 2024</strong></li>
<li>We guarantee delivery by&nbsp;<strong>December 31, 2024</strong></li>
</ul>
</div>
</div>
</div>
</div>
</div>
<div style=3D"mso-line-height-rule:exactly; line-height:150%">
<div style=3D"mso-line-height-rule:exactly; line-height:150%">
<div style=3D"mso-line-height-rule:exactly; line-height:150%">
<div data-hs-cos-general-type=3D"widget" data-hs-cos-type=3D"module" style=
=3D"mso-line-height-rule:exactly; line-height:150%">
<div data-hs-cos-general-type=3D"widget" data-hs-cos-type=3D"rich_text" sty=
le=3D"mso-line-height-rule:exactly; line-height:150%">
<p style=3D"mso-line-height-rule:exactly; line-height:150%">And don't worry=
 about installation =E2=80=93 remember, we'll be there in Q1 2025 to provid=
e two days of FREE training to make sure you start the new year like a pro.=
</p>
<p style=3D"mso-line-height-rule:exactly; line-height:150%">&nbsp;</p>
<p style=3D"mso-line-height-rule:exactly; line-height:150%">So, ring in the=
 new year with automation systems that will make your research soar!</p>
</div>
</div>
</div>
</div>
</div></div></div></td></tr></tbody></table>
</div>


    
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  <div id=3D"section-1" class=3D"hse-section" style=3D"padding-left:10px; p=
adding-right:10px">
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      <div class=3D"hse-column-container" style=3D"min-width:280px; max-wid=
th:600px; Margin-left:auto; Margin-right:auto; background-color:#ffffff" bg=
color=3D"#ffffff">
    
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<div id=3D"column-1-0" class=3D"hse-column hse-size-12">
  <table role=3D"presentation" cellpadding=3D"0" cellspacing=3D"0" width=3D=
"100%"><tbody><tr><td class=3D"hs_padded" style=3D"font-family:Arial, sans-=
serif; font-size:14px; color:#6a747c; word-break:break-word; padding:10px 2=
0px"><div id=3D"hs_cos_wrapper_module_17151177520582" class=3D"hs_cos_wrapp=
er hs_cos_wrapper_widget hs_cos_wrapper_type_module" style=3D"color: inheri=
t; font-size: inherit; line-height: inherit;" data-hs-cos-general-type=3D"w=
idget" data-hs-cos-type=3D"module"><table align=3D"center" border=3D"0" cel=
lpadding=3D"0" cellspacing=3D"0" style=3D"width:250px; background: linear-g=
radient(to right, rgba(117,172,88,1) 0%, rgba(90,158,114,1) 45%, rgba(74,15=
0,130,1) 55%, rgba(43,135,160,1) 100%); background-color:#6eb43f;" width=3D=
"250">
  <tbody>
    <tr>
      <td align=3D"center" height=3D"45" style=3D"word-break:break-word; fo=
nt-family:'ProximaNova', Arial, sans-serif; font-size:18px; color:#ffffff; =
font-weight:bold" valign=3D"middle">
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04/VWZvKy5P_ypjN6T66-F1d8t1W2v98dD5nlhlVN4zFKLx5g8s-W6N1X8z6lZ3lzVRjkH45J4p=
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pJW7h-kz81fTZ_DW88R_nt8ZWfXgW6PtcnF7Jtc1fVq3phD2h4L7hW58qB_16Fr6WcN6z2yl-T3=
cWBW514_Qf53hyZZW4z9B8271Ppv9W8McK071DRZtlW7NnRZj1z3Xn4V-wCP26Wmpf_V_Wr4d7g=
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Z16-Wn-XW4V5rNX6BZNlQW1YsdKX1H3DFsW6s_GWg4BLt-_W7h6Vxl1pvy0fW5wv8yr63MzcPW1=
-hF232t1-snW7QFzZj1sWZ22f64j4RM04" style=3D"display:block; line-height:45px=
; text-decoration:none; color:#ffffff" target=3D"_blank" rel=3D"noopener" d=
ata-hs-link-id=3D"1">
          Speak with a specialist=20
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<div id=3D"hs_cos_wrapper_module_17151132161474" class=3D"hs_cos_wrapper hs=
_cos_wrapper_widget hs_cos_wrapper_type_module" style=3D"color: inherit; fo=
nt-size: inherit; line-height: inherit;" data-hs-cos-general-type=3D"widget=
" data-hs-cos-type=3D"module"><table class=3D"hse-image-wrapper" role=3D"pr=
esentation" width=3D"100%" cellpadding=3D"0" cellspacing=3D"0">
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:center; padding:10px 20px; font-size:0px">
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      </td>
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  </tbody>
</table></div>
<div id=3D"hs_cos_wrapper_module_17314257370436" class=3D"hs_cos_wrapper hs=
_cos_wrapper_widget hs_cos_wrapper_type_module" style=3D"color: inherit; fo=
nt-size: inherit; line-height: inherit;" data-hs-cos-general-type=3D"widget=
" data-hs-cos-type=3D"module"><table class=3D"hse-image-wrapper" role=3D"pr=
esentation" width=3D"100%" cellpadding=3D"0" cellspacing=3D"0">
  <tbody>
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      <td class=3D"hs_padded" align=3D"center" valign=3D"top" style=3D"font=
-family:Arial, sans-serif; color:#6a747c; word-break:break-word; text-align=
:center; padding:10px 20px; font-size:0px">
        <a href=3D"https://email.moleculardevices.com/e3t/Ctc/OR+113/d2nr5L=
04/VWZvKy5P_ypjN6T66-F1d8t1W2v98dD5nlhlVN4zFKLd5g8s-W69t95C6lZ3npN5rSxfC6XR=
lQW5xRB522XkF6ZW7TxY7-8_nBrmW6PBRxd5hxKrJW7jHfBw3WWk8YW2CNPNS6b9Jd2W2YgDy15=
cD6Q6W2LCRqV4F7TxWVDrjN_3RTZW8VGJ-5l8PXTD6W3Q41d941TynyV2t4qh6M1VrDW442j5Y2=
qnKWgW5sxPqS1pJmC2M5Mw6RfZ8vjN3c1-QmgLhQmN2STKBBPFZ0dW68qHSw1zPmPKN96cFykVc=
vjdW7DbmjH7Bmv64W8XG8-y7rHvt-W6rCRNb3zJdtHW9d-c8173R5qfW5kmbMW6cbYHCW62SJyh=
6qTfwTW5ntmQK9llr0mW1dn_K22FPxGcW2TL4JG5tYk9HW7cH_Vv8Sc39XW90NWtY1sgl5bW8-L=
nw63N5G9ZW7Q-nsq8H8h80N7lxrxYr9F34W1fFswF864Hj7W1_2jXh6jPhbyW5DRSHg943kbvf9=
h946404" target=3D"_blank" style=3D"color:#00a4bd" data-hs-link-id=3D"0">
        <img alt=3D"T-cells and 3D Cell Models " src=3D"https://email.molec=
ulardevices.com/hs-fs/hubfs/Screenshot%202024-11-11%20at%204.28.23%20PM.png=
?width=3D1120&amp;upscale=3Dtrue&amp;name=3DScreenshot%202024-11-11%20at%20=
4.28.23%20PM.png" style=3D"outline:none; text-decoration:none; border:none;=
 max-width:100%; font-size:16px" width=3D"560" align=3D"middle">
        </a>
      </td>
    </tr>
  </tbody>
</table></div>
<table role=3D"presentation" cellpadding=3D"0" cellspacing=3D"0" width=3D"1=
00%"><tbody><tr><td class=3D"hs_padded" style=3D"font-family:Arial, sans-se=
rif; font-size:14px; color:#6a747c; word-break:break-word; padding:10px 20p=
x"><div id=3D"hs_cos_wrapper_module_17314257415187" class=3D"hs_cos_wrapper=
 hs_cos_wrapper_widget hs_cos_wrapper_type_module" style=3D"color: inherit;=
 font-size: inherit; line-height: inherit;" data-hs-cos-general-type=3D"wid=
get" data-hs-cos-type=3D"module"><div id=3D"hs_cos_wrapper_module_173142574=
15187_" class=3D"hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_r=
ich_text" style=3D"color: inherit; font-size: inherit; line-height: inherit=
;" data-hs-cos-general-type=3D"widget" data-hs-cos-type=3D"rich_text"><h2 s=
tyle=3D"margin:0; mso-line-height-rule:exactly; color:#3692ab; font-size:18=
px; line-height:150%"><span style=3D"color: #6eb43f;">T-CELLS AND 3D CELL M=
ODELS FOR IMMUNOTHERAPY</span></h2>
<h1 style=3D"margin:0; mso-line-height-rule:exactly; color:#75ac58; font-si=
ze:18px; line-height:150%"><span style=3D"color: #2b87a0;"><strong>Using th=
e power of T-cells with organoids and spheroids for cancer therapy and rese=
arch&nbsp;</strong></span></h1>
<p style=3D"mso-line-height-rule:exactly; line-height:150%">&nbsp;</p>
<p style=3D"mso-line-height-rule:exactly; line-height:150%">Immunotherapy, =
which leverages the immune system to specifically target cancer cells, is g=
aining traction as an additional form of cancer treatment. These therapies =
include CAR T-cells (Chimeric Antigen Receptor engineered T-cells), tumor-i=
nfiltrating lymphocytes (TIL), and other genetically modified T-cells.&nbsp=
;</p>
<p style=3D"mso-line-height-rule:exactly; line-height:150%">&nbsp;</p>
<p style=3D"mso-line-height-rule:exactly; line-height:150%">Enhancing T-cel=
l recruitment and cytotoxic activity is crucial for successful cancer immun=
otherapy. In preclinical scientific research, 3D cell models offer advantag=
es over 2D monolayer cultures by better mimicking the immunosuppressive tum=
or microenvironment (TME). For example, patient-derived organoids (PDOs) ar=
e superior to traditional 2D monolayer cultures because they better replica=
te the physical and chemical cues of the TME.</p></div></div></td></tr></tb=
ody></table>
<table role=3D"presentation" cellpadding=3D"0" cellspacing=3D"0" width=3D"1=
00%"><tbody><tr><td class=3D"hs_padded" style=3D"font-family:Arial, sans-se=
rif; font-size:14px; color:#6a747c; word-break:break-word; padding:10px 20p=
x"><div id=3D"hs_cos_wrapper_module_17314257484208" class=3D"hs_cos_wrapper=
 hs_cos_wrapper_widget hs_cos_wrapper_type_module" style=3D"color: inherit;=
 font-size: inherit; line-height: inherit;" data-hs-cos-general-type=3D"wid=
get" data-hs-cos-type=3D"module"><table align=3D"center" border=3D"0" cellp=
adding=3D"0" cellspacing=3D"0" style=3D"width:250px; background: linear-gra=
dient(to right, rgba(117,172,88,1) 0%, rgba(90,158,114,1) 45%, rgba(74,150,=
130,1) 55%, rgba(43,135,160,1) 100%); background-color:#6eb43f;" width=3D"2=
50">
  <tbody>
    <tr>
      <td align=3D"center" height=3D"45" style=3D"word-break:break-word; fo=
nt-family:'ProximaNova', Arial, sans-serif; font-size:18px; color:#ffffff; =
font-weight:bold" valign=3D"middle">
       =20
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        <a href=3D"https://email.moleculardevices.com/e3t/Ctc/OR+113/d2nr5L=
04/VWZvKy5P_ypjN6T66-F1d8t1W2v98dD5nlhlVN4zFKLd5g8s-W69t95C6lZ3lLW1n4T7s2YL=
BQrW4y2Vwc652P5fW5bLglW14Jx5XW4ghvmM7rvhqqW8bkrYq5YM4pNN1t3zq6RFtK1W8Jhvl03=
Y-FvBW7M6JBS6FNb7CW3Vmj1C7Lst6TW4rWkCw6m0rBjW3zJlXl16J8n1W40jZXG7M79m2W81Pz=
967JlCDCW347-5k5LQZFRW2_1nkS7QYLHtW1ZHmJY64GTfdW2n4w0D8w_R0ZW2BKWZM7RgWxxMP=
sRQdrDPfmVmqq7k8hlCScW8vb1ww1mRqSgW8_z9lb8GhpbFW14yFkS353dZdVs1QSV3RKpTvN3-=
XBShmKyNTW69D_3d1N7_VnN7JhmJLfdVy0W3zZfFR1ZkHMSW5hCqLL5376TPW2QHhWW3GDDbKW1=
6fq4_6jr1FcW6Snr6P2G2wPvN36srF3pXBc9W8Nw0Ns50S_S9W4RS71m4lxmgwW5Fd9Vm9dhDyX=
f2xWMLK04" style=3D"display:block; line-height:45px; text-decoration:none; =
color:#ffffff" target=3D"_blank" rel=3D"noopener" data-hs-link-id=3D"1">
          Explore T-cells
        </a>
      </td>
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</table></div></td></tr></tbody></table>
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hs_cos_wrapper_widget hs_cos_wrapper_type_module" style=3D"color: inherit; =
font-size: inherit; line-height: inherit;" data-hs-cos-general-type=3D"widg=
et" data-hs-cos-type=3D"module"><table class=3D"hse-image-wrapper" role=3D"=
presentation" width=3D"100%" cellpadding=3D"0" cellspacing=3D"0">
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s/hubfs/divider.png?width=3D1120&amp;upscale=3Dtrue&amp;name=3Ddivider.png"=
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th:600px; Margin-left:auto; Margin-right:auto; background-color:#ffffff" bg=
color=3D"#ffffff">
    
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<div id=3D"column_1710261300726_1" class=3D"hse-column hse-size-12">
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hs_cos_wrapper_widget hs_cos_wrapper_type_module" style=3D"color: inherit; =
font-size: inherit; line-height: inherit;" data-hs-cos-general-type=3D"widg=
et" data-hs-cos-type=3D"module"><table class=3D"hse-image-wrapper" role=3D"=
presentation" width=3D"100%" cellpadding=3D"0" cellspacing=3D"0">
  <tbody>
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      <td class=3D"hs_padded" align=3D"center" valign=3D"top" style=3D"font=
-family:Arial, sans-serif; color:#6a747c; word-break:break-word; text-align=
:center; padding:10px 20px 0px; font-size:0px">
        <a href=3D"https://email.moleculardevices.com/e3t/Ctc/OR+113/d2nr5L=
04/VWZvKy5P_ypjN6T66-F1d8t1W2v98dD5nlhlVN4zFKKF5kvg0W50kH_H6lZ3llN2xLtlfxRV=
8LW6d04tc4lCVf2W3dD6yB2wS27JW3kpGG748p5_XW1R4mLW3tSFHvW2wJP617VStf-W3jTjGL8=
_5MTCW81j2mf66kqNhW8S-G9m1XChv-W2DKpn27YVZm-W2DHX023F1z8nW2qFRjx3YpGsYN8THL=
wvhPSwJW50yXfV21XN86W2vgdKH8KnHR4W7MmDPx75P9_QW6m3Cx06cPPDLW8Wxw7g6FskqsVgX=
2w23q72yxN1TR5B-11fX7W88X2sD39BvQqW2GKLXt6GzlmlW1fK1zh10ZlsTN8rVsXYz-mDLW36=
YZLL593T1pW6tHVJP1nkvGPW67WGMg1pQ65LW8zxPpd1GGKCMW5SVQh38YTNBXW6XGNYS6xkJYK=
W4bkV_z8j1C7hW8WgmmN8_XY8Gf4wZy3l04" target=3D"_blank" style=3D"color:#00a4=
bd" data-hs-link-id=3D"0">
        <img alt=3D"DDW Article" src=3D"https://email.moleculardevices.com/=
hs-fs/hubfs/Screenshot%202024-11-12%20at%209.16.21%20AM.png?width=3D1120&am=
p;upscale=3Dtrue&amp;name=3DScreenshot%202024-11-12%20at%209.16.21%20AM.png=
" style=3D"outline:none; text-decoration:none; border:none; max-width:100%;=
 font-size:16px" width=3D"560" align=3D"middle">
        </a>
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</table></div>
<table role=3D"presentation" cellpadding=3D"0" cellspacing=3D"0" width=3D"1=
00%"><tbody><tr><td class=3D"hs_padded" style=3D"font-family:Arial, sans-se=
rif; font-size:14px; color:#6a747c; word-break:break-word; padding:17px 20p=
x 14px"><div id=3D"hs_cos_wrapper_module_17077804497989" class=3D"hs_cos_wr=
apper hs_cos_wrapper_widget hs_cos_wrapper_type_module" style=3D"color: inh=
erit; font-size: inherit; line-height: inherit;" data-hs-cos-general-type=
=3D"widget" data-hs-cos-type=3D"module"><div id=3D"hs_cos_wrapper_module_17=
077804497989_" class=3D"hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper=
_type_rich_text" style=3D"color: inherit; font-size: inherit; line-height: =
inherit;" data-hs-cos-general-type=3D"widget" data-hs-cos-type=3D"rich_text=
"><h1 style=3D"margin:0; mso-line-height-rule:exactly; color:#75ac58; font-=
size:18px; line-height:150%"><strong>NEW DRUG DISCOVERY WORLD ARTICLE&nbsp;=
</strong></h1>
<h1 style=3D"margin:0; mso-line-height-rule:exactly; color:#75ac58; font-si=
ze:18px; line-height:150%"><span style=3D"color: #2b87a0;">Are FDA plans en=
ough to boost inclusivity within clinical trials?&nbsp;&nbsp;</span></h1>
<p style=3D"mso-line-height-rule:exactly; line-height:150%">&nbsp;</p>
<p style=3D"mso-line-height-rule:exactly; line-height:150%">In an effort to=
 address diversity in clinical trials, the FDA recently issued draft guidan=
ce mandating sponsors to create Diversity Action Plans, aimed at engaging h=
istorically underrepresented populations. These plans encourage enrollment =
goals and strategies tailored to the unique needs of various communities, a=
iming to ensure therapies reflect the populations that will ultimately use =
them.</p>
<p style=3D"mso-line-height-rule:exactly; line-height:150%">&nbsp;</p>
<p style=3D"mso-line-height-rule:exactly; line-height:150%"><a href=3D"http=
s://email.moleculardevices.com/e3t/Ctc/OR+113/d2nr5L04/VWZvKy5P_ypjN6T66-F1=
d8t1W2v98dD5nlhlVN4zFKKF5kvg0W50kH_H6lZ3n7W8QLfJK3BmCsfW5s0fyW7hyYmZW6Qcphx=
3Y2d75W6PMkJZ6gZXpgW3HK5C-2-ftMbW10xmf-5tCqd8VTxnXw2QnByjN4_F7c-RQz5hW26z5Q=
l9ktvvWW91pY1t9l1SDZN72jPl2Sw2yFW7KB6SH46sQX-W8zlwwC6ghNQFW2hVMZB1sFXbDW6l2=
V6R7ZdCP9W2P_NB43Cr8GkW6w5gDg8NJY0SW63w6L07Dn66NW5SjpsK1TjkPMW77x5dn3lP3pjW=
6jvtHQ2t4qwrW7MtpMG52m1lPW8mcdZl7hlV27W7kMP5h9krMZ1V20YHh8FyLgsN1g3K3Jt6Z6h=
VrNx9S6tM9jxW5PRmLC4tw5QXW5dGGCm2mFnnDW5K5Z3140y77VW3RBY8G6Fn3J4M6y77vj2dQ5=
f5-lQtz04" style=3D"color:#00758d; text-decoration:none; font-weight:bold" =
rel=3D"noopener" data-hs-link-id=3D"1" target=3D"_blank">In this article</a=
>, Molecular Devices' VP of Strategy and Innovation, Shantanu Dhamija, emph=
asizes that advanced technologies like induced pluripotent stem cells (iPSC=
s) could help alleviate concerns about drug safety in diverse populations. =
This approach could drive greater participation by providing data on how di=
fferent demographics respond to therapies, ultimately improving access and =
outcomes across healthcare.</p></div></div></td></tr></tbody></table>
<table role=3D"presentation" cellpadding=3D"0" cellspacing=3D"0" width=3D"1=
00%"><tbody><tr><td class=3D"hs_padded" style=3D"font-family:Arial, sans-se=
rif; font-size:14px; color:#6a747c; word-break:break-word; padding:12px 20p=
x 20px"><div id=3D"hs_cos_wrapper_module_17077808148824" class=3D"hs_cos_wr=
apper hs_cos_wrapper_widget hs_cos_wrapper_type_module" style=3D"color: inh=
erit; font-size: inherit; line-height: inherit;" data-hs-cos-general-type=
=3D"widget" data-hs-cos-type=3D"module"><table align=3D"center" border=3D"0=
" cellpadding=3D"0" cellspacing=3D"0" style=3D"width:250px; background: lin=
ear-gradient(to right, rgba(117,172,88,1) 0%, rgba(90,158,114,1) 45%, rgba(=
74,150,130,1) 55%, rgba(43,135,160,1) 100%); background-color:#6eb43f;" wid=
th=3D"250">
  <tbody>
    <tr>
      <td align=3D"center" height=3D"45" style=3D"word-break:break-word; fo=
nt-family:'ProximaNova', Arial, sans-serif; font-size:18px; color:#ffffff; =
font-weight:bold" valign=3D"middle">
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        <a href=3D"https://email.moleculardevices.com/e3t/Ctc/OR+113/d2nr5L=
04/VWZvKy5P_ypjN6T66-F1d8t1W2v98dD5nlhlVN4zFKKF5kvg0W50kH_H6lZ3lRN5sZ4DjtCj=
08W35_4mC5T8Z_HMTwj8nrMR3LW3-vQ3X5cQvy7W6vYdVw2V7kr3W3vn47Q73s1lCW3p3FbW1xX=
61CVqt5HM4ZDrjXW7WfVLJ2gdtwGW1xwR1P5twY8gW6Xdm533PBHJfW6HwnV838GdjcN17yXSTS=
Cs8YW2p_NnT2KffQDW1jHhgw3SlpdHW53Yqpq4d3NkZW8plDr_8Yjw05W7dm6XZ5qnLf1W7LRGC=
V4BR433W4qmKmj52wj02W3QkcdC3CGpdqW542kR979JKF5W2V8zKX1GB38DW6f1bh95bHxZ1Vpl=
R1R5zkd2DW7yG42y4k1SjxW73S28h3YBy0WW8BLWcf3fDh0QW3D46SM2CH7G_Vb4R-c7GRYx6Vy=
RNHy4hHcX9W94_3Rj21jn8sf291qPH04" style=3D"display:block; line-height:45px;=
 text-decoration:none; color:#ffffff" target=3D"_blank" rel=3D"noopener" da=
ta-hs-link-id=3D"2">
          Read article=20
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et" data-hs-cos-type=3D"module"><table class=3D"hse-image-wrapper" role=3D"=
presentation" width=3D"100%" cellpadding=3D"0" cellspacing=3D"0">
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nZbW2ngL7j2pwlcLW2p0nV73H7gm7N15D-Lrq0r-9W7SLfXQ2qBXfBW2l15K34rhvvJW2rmp8-7=
z1c3SW5pCCHt7-8wY9VrFs3h4SVQyjW3tBRzx62h326W63CdSl2_LTVsW1Wv-Rk8KvXHLW28R69=
V5bK1ZfW7WhrRM4b6FYTW5YVwsv6x2pBmW3zRXRM7xhBLXW8qn7dV6lH5JWW340_y-27HCHBVrT=
0sB3npZgfW8mY-105-4FYcW6fq65p7TPnKnW1TCQ9k72tVYZW6L3sZJ2NnMJwW7py7_J57W8tXW=
6w6VlN3l2vQDW3RN73z19mnYhW7zYLy82ylBfgW610_DF4jrnDPW3z4PVr2LYkDjW341kkB8J_m=
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x5g8s-W6N1X8z6lZ3psW2GTjSb6szBVZW5Qy0dN1Z8PfqW8p6MgQ65C05_N2YFG1VgKZn4W6cnW=
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:center; padding:10px 20px; font-size:0px">
        <a href=3D"https://email.moleculardevices.com/e3t/Ctc/OR+113/d2nr5L=
04/VWZvKy5P_ypjN6T66-F1d8t1W2v98dD5nlhlVN4zFKKF7dJ-8W50l5tj6lZ3m-N3cCLc2wnS=
znW26SHv713DMjMW397SYL7mbjdYN3RFzctLLgt9W1rNy-n4Mzgt4W5qV2Jj91rHlnW8P_6lt9d=
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K9gy27LfWpfN9lx78vSKMBKVfgqMq4ZVL_sW6hR6tr11S_D-W70m2s73b5FQxW8zpNKd2jkG12W=
94F3MP546nrBW1JQRYg93717-W6fdTn51C0hWRW27tBSY7fxlbwW1_-JCn6_9vrDW94S2KT4fx3=
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-SN2Qf3961pZgtW3Dk7Ft5J7T64W5txxBM1-mY3-V9PP-_4Q4Lw8W43Q14y14wzlDVsRbGF8nl4=
gyf3B9HxC04" target=3D"_blank" style=3D"color:#00a4bd" data-hs-link-id=3D"0=
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5%20AM.png" style=3D"outline:none; text-decoration:none; border:none; max-w=
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left:10px; padding-right:10px">
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th:600px; Margin-left:auto; Margin-right:auto; background-color:#ffffff" bg=
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<div id=3D"column_1731424921771_0" class=3D"hse-column hse-size-12">
  <table role=3D"presentation" cellpadding=3D"0" cellspacing=3D"0" width=3D=
"100%"><tbody><tr><td class=3D"hs_padded" style=3D"font-family:Arial, sans-=
serif; font-size:14px; color:#6a747c; word-break:break-word; padding:10px 2=
0px"><div id=3D"hs_cos_wrapper_module_17314249352803" class=3D"hs_cos_wrapp=
er hs_cos_wrapper_widget hs_cos_wrapper_type_module" style=3D"color: inheri=
t; font-size: inherit; line-height: inherit;" data-hs-cos-general-type=3D"w=
idget" data-hs-cos-type=3D"module"><div id=3D"hs_cos_wrapper_module_1731424=
9352803_" class=3D"hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type=
_rich_text" style=3D"color: inherit; font-size: inherit; line-height: inher=
it;" data-hs-cos-general-type=3D"widget" data-hs-cos-type=3D"rich_text"><h1=
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<h1 style=3D"margin:0; mso-line-height-rule:exactly; color:#75ac58; font-si=
ze:18px; line-height:150%"><span style=3D"color: #2b87a0;">Increase assay r=
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<h3 style=3D"font-size:17px; margin:0; mso-line-height-rule:exactly; line-h=
eight:150%">&nbsp;</h3>
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<div data-hs-cos-general-type=3D"widget" data-hs-cos-type=3D"rich_text" sty=
le=3D"mso-line-height-rule:exactly; line-height:150%">
<p style=3D"mso-line-height-rule:exactly; line-height:150%"><a href=3D"http=
s://email.moleculardevices.com/e3t/Ctc/OR+113/d2nr5L04/VWZvKy5P_ypjN6T66-F1=
d8t1W2v98dD5nlhlVN4zFKKF7dJ-8W50l5tj6lZ3mQW5LS7ny6GbPPdW7dwPtx958cdxW3QNs4V=
8MYhf0W2mZXvl3M2M_5W6bdmTN2gMYX0W4-TntM27gnbdW1WLDp28mCF5CVLn9pZ9fpn2YW8klD=
nX6W5DgTW7NrFht2Yk1_rW2DZ9V46ywQBdW4bkTFN6yf8T7W8gm4p02ZMrkfW7B13lF8f647wW2=
2sQcG7mZNL7W4291pd86lhqmW430w6p3T4gSRW4w4P_J5s2Jm5W5N4WVW4nX8kbW4DckHv795S1=
QN4TM0-B65CW7W23r6vy8S0bgGW55bGyg2VjsLLW5Xh2jX6DCzk-W4Zmfbv8FWdB4W1TlTNX8Q-=
ZCxVcTJ-08hbBVzW20KXgW8R9kRjW59S-QZ7fwP82W6kPqL74GwdnlN4nnh9tYkkxwW44pcHH8C=
SfMJW4Lcql387dW7QW2P_-t82MqzqlW7YyF5Q5Hyh-vW7wJTqK1PswsLW7xxL4k1gX1SkW1SJt6=
Z51q7RzW13V3jS8NRgMvW6BGzMK1SJnTKW6yq10s99Y1JpN3xGYx91D2wwW2cDKC47Z0WrcW6l9=
JzL56L2GRN3Sq3-7lPTQfW8p2xLj1YH6_1W3K5px28c1Yc9W8fq5nF4nDNsXf3sJcYj04" styl=
e=3D"color:#00758d; text-decoration:none; font-weight:bold" rel=3D"noopener=
" data-hs-link-id=3D"1" target=3D"_blank">In&nbsp;this application note,</a=
> we demonstrate an in vitro model using iPSC-CMs constantly expressing a g=
enetically encoded calcium indicator for monitoring cell responses to vario=
us compounds for an extended period of time (up to 60 days).</p>
<p style=3D"mso-line-height-rule:exactly; line-height:150%">&nbsp;</p>
<p style=3D"mso-line-height-rule:exactly; line-height:150%">Additionally, a=
n optogenetic actuator was used to pace the cardiomyocytes in a noninvasive=
 and reversible manner, mimicking a physiological steady rhythm.</p>
<p style=3D"mso-line-height-rule:exactly; line-height:150%">This contactles=
s control and recording of cardiomyocytes cannot be easily achieved through=
 conventional electrical stimulation.</p>
</div>
</div>
<ul style=3D"mso-line-height-rule:exactly; line-height:150%"></ul></div></d=
iv></td></tr></tbody></table>
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      <div class=3D"hse-column-container" style=3D"min-width:280px; max-wid=
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serif; font-size:14px; color:#6a747c; word-break:break-word; padding:10px 2=
0px"><div id=3D"hs_cos_wrapper_module_17127017530652" class=3D"hs_cos_wrapp=
er hs_cos_wrapper_widget hs_cos_wrapper_type_module" style=3D"color: inheri=
t; font-size: inherit; line-height: inherit;" data-hs-cos-general-type=3D"w=
idget" data-hs-cos-type=3D"module"><table align=3D"center" border=3D"0" cel=
lpadding=3D"0" cellspacing=3D"0" style=3D"width:250px; background: linear-g=
radient(to right, rgba(117,172,88,1) 0%, rgba(90,158,114,1) 45%, rgba(74,15=
0,130,1) 55%, rgba(43,135,160,1) 100%); background-color:#6eb43f;" width=3D=
"250">
  <tbody>
    <tr>
      <td align=3D"center" height=3D"45" style=3D"word-break:break-word; fo=
nt-family:'ProximaNova', Arial, sans-serif; font-size:18px; color:#ffffff; =
font-weight:bold" valign=3D"middle">
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04/VWZvKy5P_ypjN6T66-F1d8t1W2v98dD5nlhlVN4zFKKF7dJ-8W50l5tj6lZ3pSW1KgPpn99M=
qmwW6GGbM-1X12nWW5g-vw_3X-LqyV_z-kc1JcXNNW1t15mm47k-YfW1Hd8Z_1jmnHwW56r4y57=
VxcrCW7QStBH46XTG9V66rLZ5Q6X-MW1njs8G22dQp1W2-rPNG1FbdVzW2233zl8hPF6rW7Y9TF=
v7B5DnDW3ds_t81gcqj1W4HlSYt7hbQFpW4V0vKG1PqQmpW80SRf15RwtSmN58t_5Jxh6GrW7W3=
dlJ8-CV47W63xcJs7M308pW10JKLh76_-BzW2RTdDB8wN4k8VqRvpx7vWF8_W7RjJrW57KLKwW3=
JrMs32y6rgfV279Xn48sgHlVYcy-78BGqqkW6JS_f21KnBzQW7W3dLK7bfhCRW4H5kdm5PtrpMW=
7-0ZM02g72l7W2cZnsD8yTMqJW7FmB7026WHgZW2Tl5d42ZYJfkVHgTZS93_HYhW84sY4t6SwMP=
fN4qFMrn-nNdHW4bxd6D741KCSN60hQxf9P1mlMLmbwx7NQ4XW7ZPg_h5v5hNWV3B6C38Z3wk8W=
6Z6KmK1l9HnKN274cHcx3dKTW10zdsJ8jWwlVW74Yqq43_8Dt9W1k35X13-krG_W3wKsy32cjrZ=
ff32nPcK04" style=3D"display:block; line-height:45px; text-decoration:none;=
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hs_cos_wrapper_widget hs_cos_wrapper_type_module" style=3D"color: inherit; =
font-size: inherit; line-height: inherit;" data-hs-cos-general-type=3D"widg=
et" data-hs-cos-type=3D"module"><table class=3D"hse-image-wrapper" role=3D"=
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<div id=3D"hs_cos_wrapper_module_17259794653255" class=3D"hs_cos_wrapper hs=
_cos_wrapper_widget hs_cos_wrapper_type_module" style=3D"color: inherit; fo=
nt-size: inherit; line-height: inherit;" data-hs-cos-general-type=3D"widget=
" data-hs-cos-type=3D"module"><table class=3D"hse-image-wrapper" role=3D"pr=
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ChjW3kT0vV2D4gTLW3NJtS426cXdXW5rJmV88-VK0LW28BCJs3M_HwPW3flWkW9jsxPtN1_wDn7=
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%20at%209.55.51%20AM.png" style=3D"outline:none; text-decoration:none; bord=
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  <div id=3D"section_1723489228219" class=3D"hse-section" style=3D"padding-=
left:10px; padding-right:10px">
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      <div class=3D"hse-column-container" style=3D"min-width:280px; max-wid=
th:600px; Margin-left:auto; Margin-right:auto; background-color:#ffffff" bg=
color=3D"#ffffff">
    
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<div id=3D"column_1723489228219_1" class=3D"hse-column hse-size-12">
  <table role=3D"presentation" cellpadding=3D"0" cellspacing=3D"0" width=3D=
"100%"><tbody><tr><td class=3D"hs_padded" style=3D"font-family:Arial, sans-=
serif; font-size:14px; color:#6a747c; word-break:break-word; padding:10px 2=
0px"><div id=3D"hs_cos_wrapper_module_17180520777292" class=3D"hs_cos_wrapp=
er hs_cos_wrapper_widget hs_cos_wrapper_type_module" style=3D"color: inheri=
t; font-size: inherit; line-height: inherit;" data-hs-cos-general-type=3D"w=
idget" data-hs-cos-type=3D"module"><div id=3D"hs_cos_wrapper_module_1718052=
0777292_" class=3D"hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type=
_rich_text" style=3D"color: inherit; font-size: inherit; line-height: inher=
it;" data-hs-cos-general-type=3D"widget" data-hs-cos-type=3D"rich_text"><h2=
 style=3D"margin:0; mso-line-height-rule:exactly; color:#3692ab; font-size:=
18px; line-height:150%"><span style=3D"color: #6eb43f;">NEW LAUNCH&nbsp;</s=
pan></h2>
<h2 style=3D"margin:0; mso-line-height-rule:exactly; color:#3692ab; font-si=
ze:18px; line-height:150%">We are excited to announce the launch of SoftMax=
 Pro 7.3.1 Software and SoftMax Pro 7.3.1 GxP Software Suite!</h2>
<p style=3D"mso-line-height-rule:exactly; line-height:150%">&nbsp;</p>
<p style=3D"mso-line-height-rule:exactly; line-height:150%">SoftMax=C2=AE P=
ro 7.3.1 Standard and GxP Software include several new features, formula up=
dates, and enhancements.&nbsp;</p>
<p style=3D"mso-line-height-rule:exactly; line-height:150%">&nbsp;</p>
<p style=3D"mso-line-height-rule:exactly; font-size:16px; line-height:150%"=
><span style=3D"color: #2b87a0;"><strong>Key features included in the GxP e=
dition:</strong></span></p>
<ul style=3D"mso-line-height-rule:exactly; line-height:150%">
<li>The system Audit Trail can now be exported to a .csv format.</li>
<li>Document Security enhanced to ensure all changes to SoftMax Pro documen=
ts can occur only within the application.</li>
<li>Open dialog window now displays only the folder and documents from the =
Project user are logged into.</li>
</ul>
<p style=3D"mso-line-height-rule:exactly; font-size:16px; line-height:150%"=
><span style=3D"color: #2b87a0;"><strong>Key features included in the Stand=
ard and GxP edition:</strong></span></p>
<ul style=3D"mso-line-height-rule:exactly; line-height:150%">
<li>Fully validated with Windows 11 Enterprise and Windows 11 Professional =
23H2; Windows Server 2022; Microsoft SQL Server 2022</li>
<li>Bulk Export feature features the ability to export multiple documents f=
rom different folders with included support via the Automation API.</li>
<li>Tool tips translated into Simplified Chinese.</li>
<li>The Formula Editor Check Syntax function and formula syntax have been i=
mproved to prevent an error that occurred due to the number of parentheses =
in the formula. This error became apparent after a user updated the SoftMax=
 Pro Software from a version prior to 7.3.</li>
<li>EZinCert information can now be copied and pasted from Microsoft Edge a=
nd Google Chrome</li>
</ul>
<div style=3D"mso-line-height-rule:exactly; line-height:150%">
<div style=3D"mso-line-height-rule:exactly; line-height:150%"><span style=
=3D"font-weight: bold;"> </span>
<div style=3D"mso-line-height-rule:exactly; line-height:150%"><span style=
=3D"font-weight: bold;"> </span>
<div style=3D"mso-line-height-rule:exactly; line-height:150%"><span style=
=3D"font-weight: bold;"> </span>
<div data-hs-cos-general-type=3D"widget" data-hs-cos-type=3D"module" style=
=3D"mso-line-height-rule:exactly; line-height:150%"><span style=3D"font-wei=
ght: bold;"> </span>
<div data-hs-cos-general-type=3D"widget" data-hs-cos-type=3D"rich_text" sty=
le=3D"mso-line-height-rule:exactly; line-height:150%"><span style=3D"font-w=
eight: bold;"> </span>
<div data-hs-cos-general-type=3D"widget" data-hs-cos-type=3D"module" style=
=3D"mso-line-height-rule:exactly; line-height:150%"><span style=3D"font-wei=
ght: bold;"> </span>
<div data-hs-cos-general-type=3D"widget" data-hs-cos-type=3D"rich_text" sty=
le=3D"mso-line-height-rule:exactly; line-height:150%"><span style=3D"font-w=
eight: bold;"> </span>
<p style=3D"mso-line-height-rule:exactly; line-height:150%; font-weight:bol=
d">For a detailed description on each of these new additions to this versio=
n, please refer to the&nbsp;<a href=3D"https://email.moleculardevices.com/e=
3t/Ctc/OR+113/d2nr5L04/VWZvKy5P_ypjN6T66-F1d8t1W2v98dD5nlhlVN4zFKKF5g8s-W50=
kH_H6lZ3kNW9bcfk-89Yc-TW6kCx415p0t6fW8v428X3Jc6GHW5Y3TF752mlw5W5HD6rh7p5fRn=
W7pt51Z4xWfkLW3z1SBc13xj3lW2s3n_29jFGMcW2Wp8H-5qZsm0W4LZWPQ5Lnct3W6xQ8XS3kN=
wfgW7mkWQJ6pv65GW7PTP4m907Vw7W1m7DPk2DdVYMW4FR1-h5H3fT8VbCpGD4P-ghqVK-vQ45V=
W26xW1KSWbH7JZ9jCV_W8156W1XDxW5Gkks022D7LTW6KmD_H15w--BN2krNPYV1bnCW2Dc87N2=
G0csYN4PCnNM-YcnxW1TLmQV8dJD1mW4Ml2wJ7nWHKsW5vdYdV6HqpxhVgnmpS8Yw4m6W3WtJTr=
8jR58BN1G_1qnswMbYW7SYYS05srSFWW3dFvxX10t4_Df7GZW3604" target=3D"_blank" st=
yle=3D"color:#00758d; text-decoration:none; font-weight:bold" rel=3D"noopen=
er" data-hs-link-id=3D"0">Release Notes.&nbsp;</a></p>
<span style=3D"font-weight: bold;"> </span></div>
<span style=3D"font-weight: bold;"> </span></div>
<span style=3D"font-weight: bold;"> </span></div>
<span style=3D"font-weight: bold;"> </span></div>
<span style=3D"font-weight: bold;"> </span></div>
<span style=3D"font-weight: bold;"> </span></div>
<span style=3D"font-weight: bold;"> </span></div>
<span style=3D"font-weight: bold;"> </span></div></div></div></td></tr></tb=
ody></table>
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      <div class=3D"hse-column-container" style=3D"min-width:280px; max-wid=
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<div id=3D"column-1707781525739-0" class=3D"hse-column hse-size-12">
  <table role=3D"presentation" cellpadding=3D"0" cellspacing=3D"0" width=3D=
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idget" data-hs-cos-type=3D"module"><table align=3D"center" border=3D"0" cel=
lpadding=3D"0" cellspacing=3D"0" style=3D"width:250px; background: linear-g=
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"250">
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    <tr>
      <td align=3D"center" height=3D"45" style=3D"word-break:break-word; fo=
nt-family:'ProximaNova', Arial, sans-serif; font-size:18px; color:#ffffff; =
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s2jW5-vPm51l9WWKW8zq43d76fKF8Vxrgk38YNrkcW96tKSn1LffD0W3dCsQq6WqSqgW5GlW8p5=
hmrG3V7-tHh2JGG4DW1ZFKJk8MKqkQW88DpwF7GfvvXW82dcgv5wC3dQW2P5d0W91g2xHVhtCQV=
1JlVbNW5NJw0j7c2BtSW61T11Y521HRdW24S-FP4VV5kYN6l6RcR562TdVTMgqr9ccrXGW6sq9K=
j3vHThvW722bKc8xLFt8V2wWwL9j2bQsW113WZ63X2rPwW3r6_8k7nb22QW6pFXPY2FYXc8W2Ml=
B1j5cYKPyW41W0td8gTz07W6nRGqr3NRG5MW5Sx0YF7m2XwfW5mQBb22PLmrvMNnQw8DR7FmW25=
hDGr7_tXBpW47XG2l7yLLVLW6QLZLK5zFkk4W2C2NF-2kWY6qW3F4xKN61XwtxW1QQ3nM17Mm_l=
f2gWT9204" style=3D"display:block; line-height:45px; text-decoration:none; =
color:#ffffff" target=3D"_blank" rel=3D"noopener" data-hs-link-id=3D"1">
          Update your software
        </a>
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nt-size: inherit; line-height: inherit;" data-hs-cos-general-type=3D"widget=
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serif; font-size:14px; color:#6a747c; word-break:break-word; padding:10px 2=
0px"><div id=3D"hs_cos_wrapper_module-10-0-1" class=3D"hs_cos_wrapper hs_co=
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<p style=3D"mso-line-height-rule:exactly; line-height:150%">December 14-18,=
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