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Subject: Enhance Downstream Applications with the Agilent Oligo Pro II
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DOWNLOAD THIS FREE APPLICATION NOTE
(https://email.labxmediagroup.com/e3t/Ctc/LT+113/c3tLW04/VWRz1-2fBPL_W1nkRH=
g72tv8nW2VV8NG58Z7CjN2sc1wW5m_5PW50kH_H6lZ3n2W2kVb824C-mcBW7RmK9w2lGr8kW6fP=
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GBYf2hQMdC04 )

Highlighting the capabilities for fast and automated oligo purity analysis =
prior to their use in sensitive downstream applications

The Agilent Oligo Pro II system is an automated parallel capillary electrop=
horesis instrument designed for high-throughput separation and purity analy=
sis of single-stranded DNA (ss-DNA) and RNA oligonucleotides (oligos).

The system can accommodate 12, 24, or 96 samples simultaneously, and is des=
igned to ensure oligo purity levels are achieved for downstream application=
s such as PCR, gene assembly, and microarray/hybridization assays.

This application note (https://email.labxmediagroup.com/e3t/Ctc/LT+113/c3tL=
W04/VWRz1-2fBPL_W1nkRHg72tv8nW2VV8NG58Z7CjN2sc1wW5m_5PW50kH_H6lZ3n2W2kVb824=
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3KmpDz5yjy57W8HzlzP5J3G_dW4vGgLR6K30y1W6jbH9C6xgsxwN6hW6V2G6fctM_2fmhphr2dW=
7fdDX26kGzvrW6Y09w_6b8GBYf2hQMdC04 ) describes the key performance attribut=
es of the Oligo Pro II system, including the limit of detection, nucleotide=
 resolution, impurity detection, and the impact of salt and other variables=
. Extended-length oligos as well as challenging GC-content and sequence mod=
ifications are also explored.

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hs_cos_wrapper_widget hs_cos_wrapper_type_module" style=3D"color: inherit; =
font-size: inherit; line-height: inherit;" data-hs-cos-general-type=3D"widg=
et" data-hs-cos-type=3D"module"><table class=3D"hse-image-wrapper" role=3D"=
presentation" width=3D"100%" cellpadding=3D"0" cellspacing=3D"0" style=3D"b=
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table-lspace:0pt; mso-table-rspace:0pt"><tbody><tr><td class=3D"hs_padded" =
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          <strong style=3D"color:#ffffff;font-weight:normal;text-decoration=
:none;font-style:normal;">DOWNLOAD THIS FREE APPLICATION NOTE</strong>
        </a>
      </td>
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  </tbody></table>
</div></td></tr></tbody></table>
<table role=3D"presentation" cellpadding=3D"0" cellspacing=3D"0" width=3D"1=
00%" style=3D"border-spacing:0 !important; border-collapse:collapse; mso-ta=
ble-lspace:0pt; mso-table-rspace:0pt"><tbody><tr><td class=3D"hs_padded" st=
yle=3D"border-collapse:collapse; mso-line-height-rule:exactly; font-family:=
Georgia, serif; font-size:18px; color:#23286b; word-break:break-word; paddi=
ng:10px 20px"><div id=3D"hs_cos_wrapper_module_16242852582431" class=3D"hs_=
cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_module" style=3D"colo=
r: inherit; font-size: inherit; line-height: inherit;" data-hs-cos-general-=
type=3D"widget" data-hs-cos-type=3D"module"><div id=3D"hs_cos_wrapper_modul=
e_16242852582431_" class=3D"hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wra=
pper_type_rich_text" style=3D"color: inherit; font-size: inherit; line-heig=
ht: inherit;" data-hs-cos-general-type=3D"widget" data-hs-cos-type=3D"rich_=
text"><h1 style=3D"margin:0; mso-line-height-rule:exactly; font-family:Geor=
gia, serif; color:#23286b; font-size:18px; line-height:125%; text-align:cen=
ter" align=3D"center"><span style=3D"color: #000000; font-family: Arial, sa=
ns-serif;">Highlighting the capabilities for fast and automated oligo purit=
y analysis prior to their use in sensitive downstream applications</span></=
h1>
<p style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%"=
>&nbsp;</p>
<p style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%"=
><span style=3D"color: #000000;"><span style=3D"font-family: Arial, sans-se=
rif;">The Agilent Oligo Pro II system is an automated parallel capillary el=
ectrophoresis instrument designed for high-throughput separation and purity=
 analysis of single-stranded DNA (ss-DNA) and RNA oligonucleotides (oligos)=
.</span></span></p>
<p style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%"=
>&nbsp;</p>
<p style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%"=
><span style=3D"color: #000000;"><span style=3D"font-family: Arial, sans-se=
rif;">The system can accommodate 12, 24, or 96 samples simultaneously, and =
is designed to ensure oligo purity levels are achieved for downstream appli=
cations such as PCR, gene assembly, and microarray/hybridization assays.</s=
pan></span></p>
<p style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%"=
>&nbsp;</p>
<p style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%"=
><span style=3D"color: #000000;"><span style=3D"font-family: Arial, sans-se=
rif;"><a href=3D"https://email.labxmediagroup.com/e3t/Ctc/LT+113/c3tLW04/VW=
Rz1-2fBPL_W1nkRHg72tv8nW2VV8NG58Z7CjN2sc1wW5nR32W50kH_H6lZ3kvN6qQlJh90qvNW5=
k2W8M8qdRftW9b7zZ64XvXY-VxFzVN6Kw0YyW5LmS0H5HSLbrW6m3xF35JvGsMW5H799K3Sd7TB=
W82SdLt5_jm4PW3XNBPd7Xx7N0W8drxZ58NSLnbN3_RDKpXnqWjN2pckM9f_F1vW2Lzpc76Trn1=
WW4wMB0s6cDL77W8j6fkW6GzTqLW4rw-hZ477jCgW6TP4sh2kwBrGW3QD2_F62HcvJW12X8nS4T=
VqLDW2MbYzh56tnltW50VkFz7WjJFWW98ThJ_7WR_40W81bh8Q22j01yW2r8YwN6CJCh4W4TGwH=
l75rFBNN92Zvdz7XpwqN3Zr4QllFd_xW7GBHF859MBh2W3ZPXQS2V9nSQW1fXgZy7-kxmHVRn6s=
z9hSnh1N78HX9TxSFhBf3x5X7b04" rel=3D"noopener" style=3D"mso-line-height-rul=
e:exactly; color:#929eb2" data-hs-link-id=3D"3" target=3D"_blank">This appl=
ication note</a> describes the key performance attributes of the Oligo Pro =
II system, including the limit of detection, nucleotide resolution, impurit=
y detection, and the impact of salt and other variables. Extended-length ol=
igos as well as challenging GC-content and sequence modifications are also =
explored. </span></span></p></div></div></td></tr></tbody></table>
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