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Subject: Revamp Your Lab: Faster HPLC Workflows Await!
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A Helpful Guide to Modernizing Your Old HPLC Methods

Modernizing older or compendial methods can help increase your lab=E2=80=99=
s productivity and lower your cost and carbon footprint. This guide gives y=
ou an overview of what method parameters to consider changing, as defined b=
y USP 621.

Important considerations include:

- Switching from HPLC to UHPLC
- Column particle size
- Column length and inner diameter
- Column temperature and backpressure
- Flow rates, injection volumes, and detector settings

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VWCQrt4N18JVW5fzKsv3QVkPQW6tdK5Q5gRgFBN35KTDj3qgyTW95jsWP6lZ3lXN8DF1P1sPxtl=
W1lB1dL14CfVbW4nLpmD98_J4bW5nRSnS4kNqlzW3g_lb85T-g4TW8gMl3X8p8JPsW4qjqhc7t5=
Jn-W8hqJ-w3Y1ks4W7rBjHy46N0L6N7qWMkrw67BZW5wqSB46yRcn5N7WY-pxFMQ0JW79yT6N1d=
n5KtW5hggn92-K_sVW2wBYK324lTMbW96qydD4N6BB6W7wND2B34K8mHN482VGjfbZjpN1qBzWz=
8cVLxW1QyHY43GQQ-FW6Wh3907DVGHMW3bmd209kXHG8W80RZbD56hgf8W4PWjhN11f5rJW3Mtv=
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17Ts04" target=3D"_blank" style=3D"color:#00a4bd; mso-line-height-rule:exac=
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bfs/1.1-%20All-Images/Allan%20Utton/labx%20red%20lgogo-png.png?width=3D300&=
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ame=3Dlabx%20red%20lgogo-png.png 150w, https://viewonline.labx.com/hs-fs/hu=
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hs_cos_wrapper_widget hs_cos_wrapper_type_module" style=3D"color: inherit; =
font-size: inherit; line-height: inherit;" data-hs-cos-general-type=3D"widg=
et" data-hs-cos-type=3D"module"><table class=3D"hse-image-wrapper" role=3D"=
presentation" width=3D"100%" cellpadding=3D"0" cellspacing=3D"0" style=3D"b=
order-spacing:0 !important; border-collapse:collapse; mso-table-lspace:0pt;=
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VWCQrt4N18JVW5fzKsv3QVkPQW6tdK5Q5gRgFBN35KTDj3qgyTW95jsWP6lZ3mHW44Wv7z66q87=
-W34cF7v6GNvtBW1QK11v2nJVg8W74HGxj3ktDggW38WRx38H3lmZW3N7lj26NYLGCW1411579d=
RhGrW8wycZY4W_8slVxnM041Km5rTN7QJmLwjD2P7W4jcdG48FNS4FW2tlzmw4zdx8BW2_1R2r1=
rxlLfW6kKSbd5PMLp8W5xbzGY9bm5GhW8f6F8C5XVXyLW9k-X8R4GT-sTW2DXjyy5MsmBQW2tdp=
bD6qWYc_W9kw1xD2cLB57N73yLMwV7T0xW2Scb2K16fPl_W8cGBl_1b3z5fW4mqHsv8V--rLW8h=
GWTT72fByXW7Y0_G_3WycHLW2vXv317B-Rx5W2bS0hH4fmrFgW6s9Y5J7_7J0DW1_WCvj90Wfsc=
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xactly" data-hs-link-id=3D"1">
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adding-right:10px">
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8px" bgcolor=3D"#FFFFFF">
    
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style=3D"border-collapse:collapse; mso-line-height-rule:exactly; font-famil=
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l-type=3D"widget" data-hs-cos-type=3D"module"><table align=3D"center" borde=
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Z3mBW5qGlrx8D0c1LW7QqgjF5F6bcBW5S9jl-61mNjbW4m-FBw1Dk4x6W1_py9J8Pv7X1N8fd3D=
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y6d4x63WtW6Z-khX4FysRQW7FX-0X7d-h1VW2LLcJ52JpBydVgsvS73hzCy5W8gw2C48WTDyqW6=
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  </tbody></table></div></td></tr></tbody></table>
<table role=3D"presentation" cellpadding=3D"0" cellspacing=3D"0" width=3D"1=
00%" style=3D"border-spacing:0 !important; border-collapse:collapse; mso-ta=
ble-lspace:0pt; mso-table-rspace:0pt"><tbody><tr><td class=3D"hs_padded" st=
yle=3D"border-collapse:collapse; mso-line-height-rule:exactly; font-family:=
Georgia, serif; font-size:18px; color:#23286b; word-break:break-word; paddi=
ng:10px 20px"><div id=3D"hs_cos_wrapper_module_16242852582431" class=3D"hs_=
cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_module" style=3D"colo=
r: inherit; font-size: inherit; line-height: inherit;" data-hs-cos-general-=
type=3D"widget" data-hs-cos-type=3D"module"><div id=3D"hs_cos_wrapper_modul=
e_16242852582431_" class=3D"hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wra=
pper_type_rich_text" style=3D"color: inherit; font-size: inherit; line-heig=
ht: inherit;" data-hs-cos-general-type=3D"widget" data-hs-cos-type=3D"rich_=
text"><h1 style=3D"margin:0; mso-line-height-rule:exactly; font-family:Geor=
gia, serif; color:#23286b; font-size:18px; line-height:125%; text-align:cen=
ter" align=3D"center"><span style=3D"color: #000000; font-family: Arial, sa=
ns-serif;">A Helpful Guide to Modernizing Your Old HPLC Methods</span></h1>
<p style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%"=
>&nbsp;</p>
<p style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%"=
><span style=3D"color: #000000;"><span style=3D"font-family: Arial, sans-se=
rif;">Modernizing older or compendial methods can help increase your lab=E2=
=80=99s productivity and lower your cost and carbon footprint. This guide g=
ives you an overview of what method parameters to consider changing, as def=
ined by USP 621.</span></span></p>
<p style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%"=
>&nbsp;</p>
<p style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%"=
><span style=3D"color: #000000;"><span style=3D"font-family: Arial, sans-se=
rif;">Important considerations include:</span></span></p>
<ul style=3D"mso-line-height-rule:exactly; line-height:175%; list-style-typ=
e:circle">
<li style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%=
"><span style=3D"color: #000000;"><span style=3D"font-family: Arial, sans-s=
erif;">Switching from HPLC to UHPLC</span></span></li>
<li style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%=
"><span style=3D"color: #000000;"><span style=3D"font-family: Arial, sans-s=
erif;">Column particle size</span></span></li>
<li style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%=
"><span style=3D"color: #000000;"><span style=3D"font-family: Arial, sans-s=
erif;">Column length and inner diameter</span></span></li>
<li style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%=
"><span style=3D"color: #000000;"><span style=3D"font-family: Arial, sans-s=
erif;">Column temperature and backpressure</span></span></li>
<li style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%=
"><span style=3D"color: #000000;"><span style=3D"font-family: Arial, sans-s=
erif;">Flow rates, injection volumes, and detector settings</span></span></=
li>
</ul>
<p style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%;=
 text-align:center" align=3D"center"><a href=3D"https://email.labxmediagrou=
p.com/e3t/Ctc/LT+113/c3tLW04/VWCQrt4N18JVW5fzKsv3QVkPQW6tdK5Q5gRgFBN35KTDj3=
qgyTW95jsWP6lZ3lPW355BQT6yj6GwW4LS2pB16NmDqW5hvGNz9cqPl-W6sf1D66mGQX5W7zJ7Y=
y4J9WvxW746Tvj1TJ49cN7q40R5MYhcmW4-cnz480WwSsMV0n5L-B2FmW4GhQC85HmVRvW767R1=
g76Yx2-W5FTyz12MbfK9W7dHVQC2NFNWHW81LFM_7QtRyhW2Xl8yL7Jtk4GW1jXDpm95kW_1Vwb=
Tj44T2WqHW2s6B9X3Zc3LbW1r3xxw5LXf0DN7xWkrlt94btW1w8dV798R_R9W74SPrW3cYKCrW2=
6-c_Y1ZKvDFW195vg31HGJMnW6Mvrlq2d6kjcW3kC13X20xkVzMFgVVSqwjTYW7hYP7M14_SZRW=
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">Download the free guide to learn more </span></span></a></p></div></div><=
/td></tr></tbody></table>
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