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Subject: Join Our Webinar: Master GPCR Fragment Screening for Drug Discovery
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On-Demand Webinar Event: Unlock GPCR Fragment Screening for Drug Discovery

GPCRs are notoriously difficult to study due to their intrinsic protein ins=
tability. By utilizing the sensitivity of Grating Coupled Interferometry (G=
CI) technology combined with non-clog microfluidics, these pesky membrane p=
roteins can be analyzed successfully.

Evotec, a life science company who is committed to advancing drug discovery=
 and development through their collaborations with biotech, pharma, foundat=
ions, academia and government agencies, has successfully harnessed Grating =
Coupled Interferometry (GCI) for the fragment screening of GPCRs.

Speakers

- Edoardo Fabini - Principal Scientist, Evotec
- Edward Fitzgerald - Segment Lead - Drug Discovery, Malvern Panalytical

Learning objectives include:

- What are GPCRs and why study them
- Challenges in studying GPCRs
- Evotec=E2=80=99s solution to studying GPCRs using GCI technology
- A summary of Evotec=E2=80=99s workflow and data covering:

- Assay development.
- Fragment screening
- Binding confirmation

Join this on-demand webinar event to learn more!

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  <table role=3D"presentation" cellpadding=3D"0" cellspacing=3D"0" width=3D=
"100%" class=3D"" style=3D""><tbody><tr><td class=3D"hs_padded" style=3D"fo=
nt-family:Georgia, serif; font-size:18px; color:#23286b; word-break:break-w=
ord; padding:10px 20px"><div id=3D"hs_cos_wrapper_module_16242852582431" cl=
ass=3D"hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_module" sty=
le=3D"color: inherit; font-size: inherit; line-height: inherit;" data-hs-co=
s-general-type=3D"widget" data-hs-cos-type=3D"module"><div id=3D"hs_cos_wra=
pper_module_16242852582431_" class=3D"hs_cos_wrapper hs_cos_wrapper_widget =
hs_cos_wrapper_type_rich_text" style=3D"color: inherit; font-size: inherit;=
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e=3D"rich_text"><h1 style=3D"margin:0; mso-line-height-rule:exactly; font-f=
amily:Georgia, serif; color:#23286b; font-size:18px; line-height:115%; text=
-align:center" align=3D"center"><span style=3D"color: #000000; font-family:=
 Arial, sans-serif;">On-Demand Webinar Event: Unlock GPCR Fragment Screenin=
g for Drug Discovery</span></h1>
<p style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%"=
>&nbsp;</p>
<p style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%"=
><span style=3D"color: #000000;"><span style=3D"font-family: Arial, sans-se=
rif;">GPCRs are notoriously difficult to study due to their intrinsic prote=
in instability. By utilizing the sensitivity of Grating Coupled Interferome=
try (GCI) technology combined with non-clog microfluidics, these pesky memb=
rane proteins can be analyzed successfully. </span></span></p>
<p style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%"=
>&nbsp;</p>
<p style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%"=
><span style=3D"color: #000000;"><span style=3D"font-family: Arial, sans-se=
rif;">Evotec, a life science company who is committed to advancing drug dis=
covery and development through their collaborations with biotech, pharma, f=
oundations, academia and government agencies, has successfully harnessed Gr=
ating Coupled Interferometry (GCI) for the fragment screening of GPCRs.</sp=
an></span></p>
<p style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%"=
>&nbsp;</p>
<p style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%;=
 font-weight:bold; text-align:center" align=3D"center"><span style=3D"color=
: #000000;"><span style=3D"font-family: Arial, sans-serif;">Speakers</span>=
</span></p>
<ul style=3D"mso-line-height-rule:exactly; line-height:175%">
<li style=3D"font-size: 15px; line-height: 125%;"><span style=3D"color: #00=
0000;"><span style=3D"font-family: Arial, sans-serif;">Edoardo Fabini - Pri=
ncipal Scientist, Evotec</span></span></li>
<li style=3D"font-size: 15px; line-height: 125%;"><span style=3D"color: #00=
0000;"><span style=3D"font-family: Arial, sans-serif;">Edward Fitzgerald - =
Segment Lead - Drug Discovery, Malvern Panalytical</span></span></li>
</ul>
<p style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%;=
 font-weight:bold; text-align:center" align=3D"center"><span style=3D"color=
: #000000;"><span style=3D"font-family: Arial, sans-serif;">Learning object=
ives include:</span></span></p>
<ul style=3D"mso-line-height-rule:exactly; line-height:175%">
<li style=3D"font-size: 15px; line-height: 125%;"><span style=3D"color: #00=
0000;"><span style=3D"font-family: Arial, sans-serif;">What are GPCRs and w=
hy study them</span></span></li>
<li style=3D"font-size: 15px; line-height: 125%;"><span style=3D"color: #00=
0000;"><span style=3D"font-family: Arial, sans-serif;">Challenges in studyi=
ng GPCRs</span></span></li>
<li style=3D"font-size: 15px; line-height: 125%;"><span style=3D"color: #00=
0000;"><span style=3D"font-family: Arial, sans-serif;">Evotec=E2=80=99s sol=
ution to studying GPCRs using GCI technology</span></span></li>
<li style=3D"font-size: 15px; line-height: 125%;"><span style=3D"color: #00=
0000;"><span style=3D"font-family: Arial, sans-serif;">A summary of Evotec=
=E2=80=99s workflow and data covering:</span></span>
<ul style=3D"mso-line-height-rule:exactly; line-height:175%">
<li style=3D"font-size: 15px; line-height: 125%;"><span style=3D"color: #00=
0000;"><span style=3D"font-family: Arial, sans-serif;">Assay development.</=
span></span></li>
<li style=3D"font-size: 15px; line-height: 125%;"><span style=3D"color: #00=
0000;"><span style=3D"font-family: Arial, sans-serif;">Fragment screening</=
span></span></li>
<li style=3D"font-size: 15px; line-height: 125%;"><span style=3D"color: #00=
0000;"><span style=3D"font-family: Arial, sans-serif;">Binding confirmation=
</span></span></li>
</ul>
</li>
</ul>
<p style=3D"mso-line-height-rule:exactly; font-size:15px; line-height:125%;=
 font-weight:bold; text-align:center" align=3D"center"><span style=3D"color=
: #000000;"><span style=3D"font-family: Arial, sans-serif;">Join this on-de=
mand webinar event to learn more!</span></span></p></div></div></td></tr></=
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